Impact of retroperitoneal tumors on the digestive tract (Review).

digestive tract imaging investigations retroperitoneal tumors surgical treatment urinary symptoms

Journal

Experimental and therapeutic medicine
ISSN: 1792-1015
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947

Informations de publication

Date de publication:
Dec 2022
Historique:
received: 23 07 2021
accepted: 25 08 2021
entrez: 16 11 2022
pubmed: 17 11 2022
medline: 17 11 2022
Statut: epublish

Résumé

Primary retroperitoneal tumors are a rare group of neoplasms that often prove to be a real therapeutic challenge. The clinical picture is in most cases nonspecific, being the result of nearby tissue and organ compression, displacement and/or invasion, and it usually includes a variety of deceiving signs and symptoms that may lead to diagnostic errors. During the course of the disease, up to half of the patients diagnosed with retroperitoneal tumors can develop gastrointestinal symptoms, the incidence of such symptoms significantly increasing with tumor size. Therefore, symptoms such as abdominal distension, diffuse abdominal pain or epigastric pain mimicking acute pancreatitis, diarrhea, constipation, jaundice, hematemesis, melena and hematochezia can be found. The mainstream treatment for primary retroperitoneal tumors is surgical excision, chemotherapy and radiotherapy but associated with poor results. Due to their rarity, as well as to the complexity of these tumors, patients should be managed in high volume centers that allow the possibility of a multidisciplinary approach.

Identifiants

pubmed: 36382090
doi: 10.3892/etm.2022.11647
pii: ETM-24-6-11647
pmc: PMC9634342
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

711

Informations de copyright

Copyright © 2020, Spandidos Publications.

Déclaration de conflit d'intérêts

The authors have no competing interests to declare regarding this article.

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Auteurs

Dragosradu Marcu (D)

Department of Urology, 'Dr. Carol Davila' University Emergency Central Military Hospital, 010825 Bucharest, Romania.
Department of Urology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Lucian Iorga (L)

Department of Urology, 'Dr. Carol Davila' University Emergency Central Military Hospital, 010825 Bucharest, Romania.
Department of Urology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Camelia Diaconu (C)

Department of Internal Medicine, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania.
Department of Internal Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Ovidiu Bratu (O)

Department of Urology, 'Dr. Carol Davila' University Emergency Central Military Hospital, 010825 Bucharest, Romania.
Department of Urology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Simona Bungau (S)

Department of Pharmacy, University of Oradea, Faculty of Medicine and Pharmacy, 410087 Oradea, Romania.

Irina Balescu (I)

Department of Visceral Surgery, 'Ponderas' Academic Hospital, 021188 Bucharest, Romania.

Nicolae Bacalbasa (N)

Department of Visceral Surgery, Center of Excellence in Translational Medicine, 'Fundeni' Clinical Institute, 022328 Bucharest, Romania.
Department of Obstetrics and Gynecology, 'I. Cantacuzino' Clinical Hospital, 030167 Bucharest, Romania.
Department of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Florentina Ionita Radu (FI)

Department of Gastroenterology, 'Dr. Carol Davila' University Emergency Central Military Hospital, 010825 Bucharest, Romania.

Classifications MeSH