Ageing leads to reduced specificity of antimicrobial peptide responses in
ageing
antimicrobial peptides
immune senescence
immune specificity
pathogen resistance
sexual dimorphism
Journal
Proceedings. Biological sciences
ISSN: 1471-2954
Titre abrégé: Proc Biol Sci
Pays: England
ID NLM: 101245157
Informations de publication
Date de publication:
30 11 2022
30 11 2022
Historique:
entrez:
16
11
2022
pubmed:
17
11
2022
medline:
19
11
2022
Statut:
ppublish
Résumé
Evolutionary theory predicts a late-life decline in the force of natural selection, possibly leading to late-life deregulations of the immune system. A potential outcome of such deregulations is the inability to produce specific immunity against target pathogens. We tested this possibility by infecting multiple
Identifiants
pubmed: 36382522
doi: 10.1098/rspb.2022.1642
pmc: PMC9667363
doi:
Substances chimiques
Antimicrobial Cationic Peptides
0
Antimicrobial Peptides
0
Drosophila Proteins
0
Banques de données
Dryad
['10.5061/dryad.12jm63z1s']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
20221642Références
J Immunol. 2011 Jan 15;186(2):649-56
pubmed: 21209287
Cell Host Microbe. 2009 Nov 19;6(5):446-56
pubmed: 19917499
BMC Biol. 2017 Dec 21;15(1):124
pubmed: 29268741
Proc Biol Sci. 2019 Sep 25;286(1911):20191604
pubmed: 31530150
BMC Biol. 2018 Aug 20;16(1):93
pubmed: 30124168
Proc Biol Sci. 2019 Feb 27;286(1897):20182207
pubmed: 30963836
Proc Biol Sci. 2002 Apr 22;269(1493):867-72
pubmed: 11958720
FEBS J. 2020 Jan;287(1):43-52
pubmed: 31529582
Proc Biol Sci. 2022 Nov 30;289(1987):20221642
pubmed: 36382522
Proc Biol Sci. 2006 Oct 7;273(1600):2571-4
pubmed: 16959651
Proc Biol Sci. 2017 Mar 15;284(1850):
pubmed: 28275145
Parasitol Today. 1990 Jul;6(7):231-3
pubmed: 15463350
PLoS One. 2017 May 17;12(5):e0176689
pubmed: 28520752
Nature. 2010 Mar 25;464(7288):504-12
pubmed: 20336132
Dev Comp Immunol. 2014 Jan;42(1):25-35
pubmed: 23721820
Immunity. 2020 Feb 18;52(2):374-387.e6
pubmed: 32075729
J Theor Biol. 1966 Sep;12(1):12-45
pubmed: 6015424
Cell Rep. 2017 Apr 25;19(4):836-848
pubmed: 28445733
EMBO J. 2011 Mar 16;30(6):988-90
pubmed: 21407251
J Anim Ecol. 2016 Jan;85(1):291-301
pubmed: 26257080
J Immunol. 2014 Apr 15;192(8):3455-62
pubmed: 24706930
Aging Cell. 2005 Apr;4(2):103-8
pubmed: 15771614
Elife. 2019 Feb 26;8:
pubmed: 30803481
Nat Commun. 2021 May 11;12(1):2657
pubmed: 33976227
Nat Rev Immunol. 2013 Dec;13(12):875-87
pubmed: 24157572
Virulence. 2010 Jul-Aug;1(4):295-8
pubmed: 21178458
Cell Metab. 2007 Aug;6(2):144-52
pubmed: 17681150
PLoS Pathog. 2014 Dec 04;10(12):e1004507
pubmed: 25473839
Microbes Infect. 2011 Jul;13(7):673-83
pubmed: 21354324
Science. 2016 Jul 1;353(6294):aaf3646
pubmed: 27365452
Nat Rev Immunol. 2008 Nov;8(11):889-95
pubmed: 18927577
J Exp Biol. 1994 Dec;197:421-8
pubmed: 7852912
Front Aging. 2022 May 19;3:909509
pubmed: 35821860
Proc Biol Sci. 2022 Aug 31;289(1981):20220837
pubmed: 35975433
Front Immunol. 2020 Jan 31;10:3075
pubmed: 32076419
Int Immunol. 2009 Feb;21(2):113-22
pubmed: 19088060
J Vis Exp. 2018 May 31;(135):
pubmed: 29912178
Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11414-9
pubmed: 16061818
Curr Biol. 2016 Jan 25;26(2):257-262
pubmed: 26776733
Arch Insect Biochem Physiol. 2018 Aug;98(4):e21464
pubmed: 29637607
Evol Lett. 2021 Sep 08;5(5):551-564
pubmed: 34621540
J Infect Dis. 2015 Apr 1;211(7):1174-84
pubmed: 25367297