Development of a Sensitive Anti-Human CCR9 Monoclonal Antibody (C

Mice Animals Cricetinae CHO Cells Antibodies, Monoclonal Cricetulus T-Lymphocytes Immunization
flow cytometry human CCR9 monoclonal antibody western blot

Journal

Monoclonal antibodies in immunodiagnosis and immunotherapy
ISSN: 2167-9436
Titre abrégé: Monoclon Antib Immunodiagn Immunother
Pays: United States
ID NLM: 101590955

Informations de publication

Date de publication:
Dec 2022
Historique:
pubmed: 17 11 2022
medline: 31 12 2022
entrez: 16 11 2022
Statut: ppublish

Résumé

The C-C chemokine receptor 9 (CCR9) belongs to the G-protein-coupled receptor superfamily, and is highly expressed on the T cells and intestinal cells. CCR9 regulates various immune responses by binding to the C-C chemokine ligand, CCL25, and is involved in inflammatory diseases and tumors. Therefore, the development of sensitive monoclonal antibodies (mAbs) for CCR9 is necessary for treatment and diagnosis. In this study, we established a specific anti-human CCR9 (hCCR9) mAb; C

Identifiants

DOI: 10.1089/mab.2022.0027 PMID: 36383113
pubmed: 36383113
doi: 10.1089/mab.2022.0027
doi:

Substances chimiques

Antibodies, Monoclonal 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

303-310

Auteurs

Tomohiro Tanaka (T)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Hiroyuki Suzuki (H)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Yu Isoda (Y)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Teizo Asano (T)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Takuro Nakamura (T)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Miyuki Yanaka (M)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Saori Handa (S)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Nozomi Takahashi (N)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Saori Okuno (S)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Takeo Yoshikawa (T)

Department of Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.
ORCID: 0000-0002-7056-6021

Guanjie Li (G)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Ren Nanamiya (R)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Nohara Goto (N)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Nami Tateyama (N)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Yuki Okada (Y)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Hiyori Kobayashi (H)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Mika K Kaneko (MK)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Yukinari Kato (Y)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.
ORCID: 0000-0001-5385-8201

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Development of a Sensitive Anti-Human CCR9...
questionsmedicales.fr › Eucaryotes › Animaux › Development of a Sensitive Anti-Human CCR9...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Development of a Sensitive Anti-Human CCR9...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules CHO › Development of a Sensitive Anti-Human CCR9...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Development of a Sensitive Anti-Human CCR9...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Cricetulus › Development of a Sensitive Anti-Human CCR9...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Development of a Sensitive Anti-Human CCR9...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Immunisation › Development of a Sensitive Anti-Human CCR9...