Global disparities in SARS-CoV-2 genomic surveillance.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
16 11 2022
16 11 2022
Historique:
received:
29
01
2022
accepted:
29
09
2022
entrez:
17
11
2022
pubmed:
18
11
2022
medline:
22
11
2022
Statut:
epublish
Résumé
Genomic sequencing is essential to track the evolution and spread of SARS-CoV-2, optimize molecular tests, treatments, vaccines, and guide public health responses. To investigate the global SARS-CoV-2 genomic surveillance, we used sequences shared via GISAID to estimate the impact of sequencing intensity and turnaround times on variant detection in 189 countries. In the first two years of the pandemic, 78% of high-income countries sequenced >0.5% of their COVID-19 cases, while 42% of low- and middle-income countries reached that mark. Around 25% of the genomes from high income countries were submitted within 21 days, a pattern observed in 5% of the genomes from low- and middle-income countries. We found that sequencing around 0.5% of the cases, with a turnaround time <21 days, could provide a benchmark for SARS-CoV-2 genomic surveillance. Socioeconomic inequalities undermine the global pandemic preparedness, and efforts must be made to support low- and middle-income countries improve their local sequencing capacity.
Identifiants
pubmed: 36385137
doi: 10.1038/s41467-022-33713-y
pii: 10.1038/s41467-022-33713-y
pmc: PMC9667854
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
7003Subventions
Organisme : NHLBI NIH HHS
ID : T35 HL007649
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI153044
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : Medical Research Council
ID : MR/S019510/1
Pays : United Kingdom
Organisme : World Health Organization
ID : 001
Pays : International
Organisme : Medical Research Council
ID : MR/R015600/1
Pays : United Kingdom
Investigateurs
Todor Kantardjiev
(T)
Nelly Korsun
(N)
Savina Stoitsova
(S)
Reneta Dimitrova
(R)
Ivelina Trifonova
(I)
Veselin Dobrinov
(V)
Lubomira Grigorova
(L)
Ivan Stoykov
(I)
Iliana Grigorova
(I)
Anna Gancheva
(A)
Amy Jennison
(A)
Lex Leong
(L)
David Speers
(D)
Rob Baird
(R)
Louise Cooley
(L)
Karina Kennedy
(K)
Joep de Ligt
(J)
William Rawlinson
(W)
Sebastiaan van Hal
(S)
Deborah Williamson
(D)
Risha Singh
(R)
SueMin Nathaniel-Girdharrie
(S)
Lisa Edghill
(L)
Lisa Indar
(L)
Joy St John
(J)
Gabriel Gonzalez-Escobar
(G)
Vernie Ramkisoon
(V)
Arianne Brown-Jordan
(A)
Anushka Ramjag
(A)
Nicholas Mohammed
(N)
Jerome E Foster
(JE)
Irad Potter
(I)
Sharra Greenaway-Duberry
(S)
Kenneth George
(K)
Sharon Belmar-George
(S)
John Lee
(J)
Jacqueline Bisasor-McKenzie
(J)
Nadia Astwood
(N)
Rhonda Sealey-Thomas
(R)
Hazel Laws
(H)
Narine Singh
(N)
Ayoola Oyinloye
(A)
Pearl McMillan
(P)
Avery Hinds
(A)
Naresh Nandram
(N)
Roshan Parasram
(R)
Zobida Khan-Mohammed
(Z)
Shawn Charles
(S)
Aisha Andrewin
(A)
David Johnson
(D)
Simone Keizer-Beache
(S)
Chris Oura
(C)
Oliver G Pybus
(OG)
Nuno R Faria
(NR)
Marc Stegger
(M)
Mads Albertsen
(M)
Anders Fomsgaard
(A)
Morten Rasmussen
(M)
Ricardo Khouri
(R)
Felipe Naveca
(F)
Tiago Graf
(T)
Fábio Miyajima
(F)
Gabriel Wallau
(G)
Fernando Motta
(F)
Shruti Khare
(S)
Lucas Freitas
(L)
Constanza Schiavina
(C)
Gunter Bach
(G)
Mark B Schultz
(MB)
Yi Hong Chew
(YH)
Meera Makheja
(M)
Priscila Born
(P)
Gabriela Calegario
(G)
Sofia Romano
(S)
Juan Finello
(J)
Amadou Diallo
(A)
Raphael T C Lee
(RTC)
Ya Ni Xu
(YN)
Winston Yeo
(W)
Suma Tiruvayipati
(S)
Shilpa Yadahalli
(S)
Eduan Wilkinson
(E)
Arash Iranzadeh
(A)
Jennifer Giandhari
(J)
Deelan Doolabh
(D)
Sureshnee Pillay
(S)
Upasana Ramphal
(U)
James E San
(JE)
Nokukhanya Msomi
(N)
Koleka Mlisana
(K)
Anne von Gottberg
(A)
Sibongile Walaza
(S)
Arshad Ismail
(A)
Thabo Mohale
(T)
Susan Engelbrecht
(S)
Gert Van Zyl
(G)
Wolfgang Preiser
(W)
Alex Sigal
(A)
Diana Hardie
(D)
Gert Marais
(G)
Marvin Hsiao
(M)
Stephen Korsman
(S)
Mary-Ann Davies
(MA)
Lynn Tyers
(L)
Innocent Mudau
(I)
Denis York
(D)
Caroline Maslo
(C)
Dominique Goedhals
(D)
Shareef Abrahams
(S)
Oluwakemi Laguda-Akingba
(O)
Arghavan Alisoltani-Dehkordi
(A)
Adam Godzik
(A)
Constantinos K Wibmer
(CK)
Darren Martin
(D)
Richard J Lessells
(RJ)
Jinal N Bhiman
(JN)
Carolyn Williamson
(C)
Tulio de Oliveira
(T)
Chaoran Chen
(C)
Sarah Nadeau
(S)
Louis du Plessis
(L)
Christiane Beckmann
(C)
Maurice Redondo
(M)
Olivier Kobel
(O)
Christoph Noppen
(C)
Sophie Seidel
(S)
Noemie Santamaria de Souza
(NS)
Niko Beerenwinkel
(N)
Ivan Topolsky
(I)
Philipp Jablonski
(P)
Lara Fuhrmann
(L)
David Dreifuss
(D)
Katharina Jahn
(K)
Pedro Ferreira
(P)
Susana Posada-Céspedes
(S)
Christian Beisel
(C)
Rebecca Denes
(R)
Mirjam Feldkamp
(M)
Ina Nissen
(I)
Natascha Santacroce
(N)
Elodie Burcklen
(E)
Catharine Aquino
(C)
Andreia Cabral de Gouvea
(AC)
Maria Domenica Moccia
(MD)
Simon Grüter
(S)
Timothy Sykes
(T)
Lennart Opitz
(L)
Griffin White
(G)
Laura Neff
(L)
Doris Popovic
(D)
Andrea Patrignani
(A)
Jay Tracy
(J)
Ralph Schlapbach
(R)
Emmanouil Dermitzakis
(E)
Keith Harshman
(K)
Ioannis Xenarios
(I)
Henri Pegeot
(H)
Lorenzo Cerutti
(L)
Deborah Penet
(D)
Tanja Stadler
(T)
Commentaires et corrections
Type : UpdateOf
Informations de copyright
© 2022. The Author(s).
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