Assessment of health-related quality of life in individuals with depressive symptoms: validity and responsiveness of the EQ-5D-3L and the SF-6D.

Humans Quality of Life Depression Surveys and Questionnaires Mental Disorders Psychometrics Reproducibility of Results
EQ-5D-3L Mental disorder Responsiveness SF-6D Validity

Journal

The European journal of health economics : HEPAC : health economics in prevention and care
ISSN: 1618-7601
Titre abrégé: Eur J Health Econ
Pays: Germany
ID NLM: 101134867

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 24 05 2022
accepted: 24 10 2022
medline: 23 10 2023
pubmed: 18 11 2022
entrez: 17 11 2022
Statut: ppublish

Résumé

The EQ-5D and the SF-6D are examples of commonly used generic preference-based instruments for assessing health-related quality of life (HRQoL). However, their suitability for mental disorders has been repeatedly questioned. To assess the responsiveness and convergent validity of the EQ-5D-3L and SF-6D in patients with depressive symptoms. The data analyzed were from cardiac patients with depressive symptoms and were collected as part of the SPIRR-CAD (Stepwise Psychotherapy Intervention for Reducing Risk in Coronary Artery Disease) trial. The EQ-5D-3L and SF-6D were compared with the HADS (Hospital Anxiety and Depression Scale) and PHQ-9 (Patient Health Questionnaire) as disease-specific instruments. Convergent validity was assessed using Spearman's rank correlation. Effect sizes were calculated and ROC analysis was performed to determine responsiveness. Data from 566 patients were analysed. The SF-6D correlated considerably better with the disease-specific instruments (|r Overall, both the convergent validity and responsiveness of the SF-6D are better than those of the EQ-5D-3L in patients with depressive symptoms. The SF-6D appears, therefore, more recommendable for use in studies to evaluate interventions for this population.

Sections du résumé

BACKGROUND BACKGROUND
The EQ-5D and the SF-6D are examples of commonly used generic preference-based instruments for assessing health-related quality of life (HRQoL). However, their suitability for mental disorders has been repeatedly questioned.
OBJECTIVE OBJECTIVE
To assess the responsiveness and convergent validity of the EQ-5D-3L and SF-6D in patients with depressive symptoms.
METHODS METHODS
The data analyzed were from cardiac patients with depressive symptoms and were collected as part of the SPIRR-CAD (Stepwise Psychotherapy Intervention for Reducing Risk in Coronary Artery Disease) trial. The EQ-5D-3L and SF-6D were compared with the HADS (Hospital Anxiety and Depression Scale) and PHQ-9 (Patient Health Questionnaire) as disease-specific instruments. Convergent validity was assessed using Spearman's rank correlation. Effect sizes were calculated and ROC analysis was performed to determine responsiveness.
RESULTS RESULTS
Data from 566 patients were analysed. The SF-6D correlated considerably better with the disease-specific instruments (|r
CONCLUSION CONCLUSIONS
Overall, both the convergent validity and responsiveness of the SF-6D are better than those of the EQ-5D-3L in patients with depressive symptoms. The SF-6D appears, therefore, more recommendable for use in studies to evaluate interventions for this population.

Identifiants

DOI: 10.1007/s10198-022-01543-w PMID: 36385438 PMC: PMC10533591
pubmed: 36385438
doi: 10.1007/s10198-022-01543-w
pii: 10.1007/s10198-022-01543-w
pmc: PMC10533591
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1297-1307

Informations de copyright

© 2022. The Author(s).

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Auteurs

Maike Stolz (M)

Institute of Epidemiology Social Medicine and Health System Research, Hannover Medical School, Hanover, Germany. stolz.maike@mh-hannover.de.
Center for Health Economics Research Hanover (CHERH), Hanover, Germany. stolz.maike@mh-hannover.de.

Christian Albus (C)

Department of Psychosomatics and Psychotherapy, University of Cologne, Cologne, Germany.

Manfred E Beutel (ME)

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Mainz, Germany.

Hans-Christian Deter (HC)

Department of Psychosomatics and Psychotherapy, Charité Universitaetsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.

Kurt Fritzsche (K)

Faculty of Medicine, Department of Psychosomatic Medicine and Psychotherapy, Medical Center-University of Freiburg, Freiburg, Germany.

Christoph Herrmann-Lingen (C)

Department of Psychosomatic Medicine and Psychotherapy, University of Göttingen Medical Center, Göttingen, Germany.
German Center for Cardiovascular Research (DZHK), Partner Site Göttingen, Göttingen, Germany.

Matthias Michal (M)

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Mainz, Germany.

Katja Petrowski (K)

Department of Psychotherapy and Psychosomatics, Technical University of Dresden, Dresden, Germany.

Joram Ronel (J)

Department of Psychosomatic Medicine and Psychotherapy, Clinic Barmelweid, Barmelweid, Switzerland.
Department of Psychosomatic Medicine and Psychotherapy, University Hospital Rechts Der Isar, Technische Universitaet München, Munich, Germany.

Jobst-Hendrik Schultz (JH)

Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.

Wolfgang Söllner (W)

Department of Psychosomatic Medicine and Psychotherapy, Paracelsus Medical University Nuremberg, Nuremberg, Germany.

Cora Weber (C)

Department of Psychosomatic Medicine and Psychotherapy, Oberhavel Clinic, Clinic Hennigsdorf, Hennigsdorf, Germany.

Martina de Zwaan (M)

Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hanover, Germany.

Christian Krauth (C)

Institute of Epidemiology Social Medicine and Health System Research, Hannover Medical School, Hanover, Germany.
Center for Health Economics Research Hanover (CHERH), Hanover, Germany.

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