Effects of single rinse with three different types of mouthwashes on VSCs levels in morning breath: Randomized, double-blind, crossover clinical trial.
halitosis
morning breath
mouthwash
oral chroma
oral malodour
Journal
International journal of dental hygiene
ISSN: 1601-5037
Titre abrégé: Int J Dent Hyg
Pays: England
ID NLM: 101168070
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
revised:
21
09
2022
received:
17
08
2021
accepted:
15
11
2022
medline:
4
4
2023
pubmed:
18
11
2022
entrez:
17
11
2022
Statut:
ppublish
Résumé
Morning breath is a temporary and unpleasant malodour sourced from the mouth, which occurs upon awakening. This double-blind, crossover, randomized clinical trial aimed to evaluate the bad-breath suppression of three commercially available mouthwashes: Mentadent Professional® Chlorhexidine 0.05% with vitamin C (ChxC), Meridol Alito Sicuro® (SnF Thirty-two subjects refraining from oral hygiene practices for 12 h before the evaluation, performed a 30-s rinse with 15 ml of mouthwash, followed by a 5-s gargle, in the evening before bedtime. In order to assess morning halitosis, visual inspection (Winkel Tongue Coating Index), organoleptic (Rosenberg index) and chromatographic measurements were used. Gas chromatography was carried out by means of a dedicated device, the Oral Chroma. The recorded measurements have to be considered solely after the rinse since no data about the pre-exposure were available. A washout period of 1 week passed between one administration and the next. The mean value of the organoleptic indices after administration of ChxC mouthwash is similar to ZnChx, SnF Considering our limited sample, instrumental examination demonstrated that the use of the analysed mouthwashes can result in low VSCs levels after 12 h from a single rinse. Furthermore, the highest number of patients (n = 14) were proved to be free from bad smell after using a single administration of ChxC with respect to the other commercial products. The other tested mouthwashes did not show better performances with respect to the placebo after a single rinse.
Substances chimiques
Mouthwashes
0
Chlorhexidine
R4KO0DY52L
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
417-425Informations de copyright
© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Références
Tonzetich J. Production and origin of Oral malodor: a review of mechanisms and methods of analysis. J Periodontol. 1977;48:13-20.
Delanghe G, Ghyselen J, Van Steenberghe D, Feenstra L. Multidisciplinary breath-odour clinic. Lancet. 1997;350:187.
Tangerman A. Halitosis in medicine: a review. Int Dent J. 2002;52:201-206.
Porter SR, Scully C. Oral malodour (halitosis). BMJ. 2006;333:632-635.
Seemann R, Conceicao MD, Filippi A, et al. Halitosis management by the general dental practitioner-results of an international consensus workshop. J Breath Res. 2014;8(1):017101.
Evirgen S, Kamburoğlu K, Gulsahi A. Effect of clinician's experience, age, gender and calibration on the assessment of halitosis. Oral Health Prev Dent. 2013;11(1):17-22.
Rosenberg M, McCulloch CAG. Measurement of Oral malodor: current methods and future prospects. J Periodontol. 1992;63:776-782.
Danser MM, Gómez SM, Van der Weijden GA. Tongue coating and tongue brushing: a literature review. Int J Dent Hyg. 1992;1:151-158.
Van der Sluijs E, Slot D, Bakker E, Van der Weijden G. The effect of water on morning bad breath: a randomized clinical trial. Int J Dent Hyg. 2016;14:124-134.
van Steenberghe D, Avontroodt P, Peeters W, et al. Effect of different Mouthrinses on morning breath. J Periodontol. 2001;72:1183-1191.
Slot DE, De Geest S, van der Weijden FA, Quirynen M. Treatment of oral malodour. Medium-term efficacy of mechanical and/or chemical agents: a systematic review. J Clin Periodontol. 2015;42(Suppl 16):S303-S316.
Delanghe G, Ghyselen J, Bollen C, Van Steenberghe D, Vandekerckhove BNA, Feenstra L. An inventory of patients' response to treatment at a multidisciplinary breath odor clinic. Quintessence Int. 1999;30:307-310.
Söder B, Johansson B, Söder PÖ. The relation between foetor ex ore, oral hygiene and periodontal disease. Swed Dent J. 2000;24:73-82.
Miyazaki H, Sakao S, Katoh Y, Takehara T. Correlation between volatile Sulphur compounds and certain oral health measurements in the general population. J Periodontol. 1995;66:679-684.
Aimetti M, Perotto S, Castiglione A, Ercoli E, Romano F. Prevalence estimation of halitosis and its association with oral health-related parameters in an adult population of a city in North Italy. J Clin Periodontol. 2015;42(12):1105-1114.
Carvalho MD, Tabchoury CM, Cury JA, Toledo S, Nogueira-Filho GR. Impact of mouthrinses on morning bad breath in healthy subjects. J Clin Periodontol. 2004;31(2):85-90.
Niwa M, Saito K, Suganuma N, Watanabe H, Sawamura K. A study on the deodorant effect of dentifrices containing chlorhexidine. Koku Eisei Gakkai Zasshi. 1977;27(2):79-89.
Marchetti E, Tecco S, Caterini E, et al. Alcohol-free essential oils containing mouthrinse efficacy on three-day supragingival plaque regrowth: a randomized crossover clinical trial. Trials. 2017;18:154p.
Marchetti E, Casalena F, Capestro A, Tecco S, Mattei A, Marzo G. Efficacy of two mouthwashes on 3-day supragingival plaque regrowth: a randomized crossover clinical trial. Int J Dent Hyg. 2017;15:73-80.
Wu J, Cannon RD, Ji P, Farella M, Mei L. Halitosis: prevalence, risk factors, sources, measurement and treatment-a review of the literature. Aust Dent J. 2020;65:4-11.
Young A, Jonsky G. Effect of a single brushing with two Zn-containing toothpastes on VSC in morning breath: a 12 h, randomized, double-blind, cross-over clinical study. J Breath Res. 2011;5:046012.
Cohen J. A power primer. Psychol Bull. 1992;112(1):155-159.
Primal KS, Esther SR, Boehm TK. Periodontal screening and recording (PSR) index scores predict periodontal diagnosis. J Dent App. 2014;1(1):8-12.
Bescos R, Ashworth A, Cutler C, et al. Effects of chlorhexidine mouthwash on the oral microbiome. Sci Rep. 2020;10:5254.
Fine DH. Chemical agents to prevent and regulate plaque development. Periodontol. 1995;8:87-107.
Cortelli JR, Barbosa MDS, Westphal MA. Halitosis: a review of associated factors and therapeutic approach. Braz Oral Res. 2008;22(suppl.1):44-54.
Armstrong BL, Sensat ML, Stoltenberg JL. Halitosis: a review of current literature. J Dent Hyg. 2010;84:65-74.
Takeshita T, Suzuki N, Nakano Y, et al. Discrimination of the oral microbiota associated with high hydrogen sulfide and methyl mercaptan production. Sci Rep. 2012;2:215.
Lee CH, Kho HS, Chung SC, Lee SW, Kim YK. The relationship between volatile sulfur compounds and major halitosis-inducing factors. J Periodontol. 2003;74(1):32-37.
Aylıkcı BU, Colak H. Halitosis: from diagnosis to management. J Nat Sci Biol Med. 2013;4(1):14-23.
Loesche WJ, Kazor C. Microbiology and treatment of halitosis. Periodontol. 2002;28:256-279.
Thrane PS, Young A, Jonski G, Rölla G. A new mouthrinse combining zinc and chlorhexidine in low concentrations provides superior efficacy against halitosis compared to existing formulations: a double-blind clinical study. J Clin Dent. 2007;18:82-86.
Thrane PS, Jonski G, Young A, Rölla G. Zn and CHX mouthwash effective against VSCs responsible for halitosis for up to 12 hours. Dent Health. 2009;48:8-12.
Saad S, Greenman J, Shaw H. Comparative effects of various commercially available mouthrinse formulations on oral malodour. Oral Dis. 2011;17:180-186.
Brecx M, MacDonald LL, Legary K, Cheang M. Long-term effects of Meridol® and chlorhexidine Mouthrinses on plaque, gingivitis, staining, and bacterial vitality. J Dent Res. 1993;72:1194-1197.
Auschill TM, Hein N, Hellwig E, Follo M, Sculean A, Arweiler NB. Effect of two antimicrobial agents on early in situ biofilm formation. J Clin Periodontol. 2005;32:147-152.
Wigger-Alberti W, Gysen K, Axmann EM, Wilhelm KP. Efficacy of a new mouthrinse formulation on the reduction of oral malodour in vivo. A randomized, double-blind, placebo-controlled, 3 weeks clinical study. J Breath Res. 2010;4(1):017102.
Wilhelm D, Gysen K, Himmelmann A, Krause C, Wilhelm KP. Short-term effect of a new mouthrinse formulation on oral malodour after single use in vivo: a comparative, randomized, single-blind, parallel-group clinical study. J Breath Res. 2010;4(3):036002.
Schmidt NF, Tarbet WJ. The effect of oral rinses on organoleptic mouth odor ratings and levels of volatile sulfur compounds. Oral Surg Oral Med Oral Pathol. 1978;45:876-883.
Dobler D, Runkel F, Schmidts T. Effect of essential oils on oral halitosis treatment: a review. Eur J Oral Sci. 2020;128(6):476-486.
Kolliyavar B, Thakur S, Shettar L. Chlorhexidine: the gold standard mouth wash. J Pharm Biomed Sci. 1978;6:23-26.
Mathur S, Mathur T, Rahul Srivastava RK. Chlorhexidine: the gold standard in chemical plaque control. Natl J Physiol Pharm Pharmacol. 2011;1:45-50.
Balagopal Shruti AR. Chlorhexidine: the gold standard antiplaque agent. J Pharm Sci Res. 2011;5:270-274.
Mousavi S, Bereswill S, Heimesaat MM. Immunomodulatory and antimicrobial effects of vitamin C. Eur J Microbiol Immunol. 2019;9:73-79.
Freeman DE, Auer JA. Instrument preparation, sterilization, and antiseptics (Chapter 9). Equine Surgery. Fourth ed. W.B. Saunders; 2012:98-111.
Tada A, Miura H. The relationship between vitamin C and periodontal diseases: a systematic review. Int J Environ Res Public Health. 2019;16:2472.
Fageeh HN, Fageeh HI, Prabhu A, Bhandi S, Khan S, Patil S. Efficacy of vitamin C supplementation as an adjunct in the non-surgical management of periodontitis: a systematic review. Syst Rev. 2021;10:5.
Bogdan M, Meca AD, Boldeanu MV, et al. Possible involvement of vitamin C in periodontal disease-diabetes mellitus association. Nutrients. 2020;12(2):553.