Successful pregnancy in a cystic fibrosis patient with a severe impairment of lung function receiving Elexacaftor-Tezacaftor-Ivacaftor.
Cystic fibrosis
Elexacaftor-Tezacaftor-Ivacaftor
Impaired lung function
Pregnancy
Journal
Respiratory medicine case reports
ISSN: 2213-0071
Titre abrégé: Respir Med Case Rep
Pays: England
ID NLM: 101604463
Informations de publication
Date de publication:
2022
2022
Historique:
received:
11
09
2022
accepted:
06
11
2022
entrez:
17
11
2022
pubmed:
18
11
2022
medline:
18
11
2022
Statut:
epublish
Résumé
Before the arrival of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulators women with CF and impaired lung function were experiencing a high risk of complications and mortality during and the years after pregnancy. The arrival of the highly efficient CFTR modulator, Elexacaftor-Tezacaftor-Ivacaftor (ETI) resulted in an improvement of lung function, quality of life and fertility. Here we report a case of successful pregnancy and uncomplicated delivery for a CF patient with severely impaired lung function receiving ETI prior to conception.
Identifiants
pubmed: 36386288
doi: 10.1016/j.rmcr.2022.101776
pii: S2213-0071(22)00198-8
pmc: PMC9664010
doi:
Types de publication
Case Reports
Langues
eng
Pagination
101776Informations de copyright
© 2022 The Authors. Published by Elsevier Ltd.
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