Transfer learning-based modified inception model for the diagnosis of Alzheimer's disease.

Alzheimer's disease classification confusion matrix feature visualization modified inception

Journal

Frontiers in computational neuroscience
ISSN: 1662-5188
Titre abrégé: Front Comput Neurosci
Pays: Switzerland
ID NLM: 101477956

Informations de publication

Date de publication:
2022
Historique:
received: 22 07 2022
accepted: 29 08 2022
entrez: 17 11 2022
pubmed: 18 11 2022
medline: 18 11 2022
Statut: epublish

Résumé

Alzheimer's disease (AD) is a neurodegenerative ailment, which gradually deteriorates memory and weakens the cognitive functions and capacities of the body, such as recall and logic. To diagnose this disease, CT, MRI, PET, etc. are used. However, these methods are time-consuming and sometimes yield inaccurate results. Thus, deep learning models are utilized, which are less time-consuming and yield results with better accuracy, and could be used with ease. This article proposes a transfer learning-based modified inception model with pre-processing methods of normalization and data addition. The proposed model achieved an accuracy of 94.92 and a sensitivity of 94.94. It is concluded from the results that the proposed model performs better than other state-of-the-art models. For training purposes, a Kaggle dataset was used comprising 6,200 images, with 896 mild demented (M.D) images, 64 moderate demented (Mod.D) images, and 3,200 non-demented (N.D) images, and 1,966 veritably mild demented (V.M.D) images. These models could be employed for developing clinically useful results that are suitable to descry announcements in MRI images.

Identifiants

pubmed: 36387304
doi: 10.3389/fncom.2022.1000435
pmc: PMC9664223
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1000435

Informations de copyright

Copyright © 2022 Sharma, Gupta, Gupta, Juneja, Mahmoud, El–Sappagh and Kwak.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Sarang Sharma (S)

Department of Computer Science and Engineering, Chitkara University Institute of Engineering and Technology, Chandigarh, Punjab, India.

Sheifali Gupta (S)

Department of Computer Science and Engineering, Chitkara University Institute of Engineering and Technology, Chandigarh, Punjab, India.

Deepali Gupta (D)

Department of Computer Science and Engineering, Chitkara University Institute of Engineering and Technology, Chandigarh, Punjab, India.

Sapna Juneja (S)

Department of Computer Science, KIET Group of Institutions, Ghaziabad, India.

Amena Mahmoud (A)

Department of Computer Science, Kafrelsheikh University, Kafr el-Sheikh, Egypt.

Shaker El-Sappagh (S)

Faculty of Computer Science and Engineering, Galala University, Suez, Egypt.
Information Systems Department, Faculty of Computers and Artificial Intelligence, Benha University, Banha, Egypt.

Kyung-Sup Kwak (KS)

Department of Information and Communication Engineering, Inha University, Incheon, South Korea.

Classifications MeSH