Primary spinal Non-Hodgkin Lymphoma presenting as impending cauda equina syndrome: A case report.
Case report
Decompression
Diffuse large B cell Lymphoma
Non-hodgkin lymphoma
Primary spinal lymphoma
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
received:
07
07
2022
revised:
05
09
2022
accepted:
09
09
2022
entrez:
17
11
2022
pubmed:
18
11
2022
medline:
18
11
2022
Statut:
epublish
Résumé
Malignant lymphoma (ML) can involve the central nervous system either primarily or by secondary spread, which tends to occur late in the disease as part of widespread dissemination. Lymphoma presenting as primary tumors of the spinal cord is extremely uncommon. Primary spinal lymphoma if detected early can have a good prognosis with no relapse after effective treatment. A 32 years old male patient presented with the symptoms of impending cauda equina syndrome which was managed with surgery and chemotherapy. The patient was successfully treated without the relapse of his condition at his 6 months follow-up scan.Discussion: Primary spinal non-Hodgkin lymphoma is a rare entity among extranodal non-Hodgkin lymphoma. MRI is usually non-confirmatory and needs immunohistochemistry for the correct diagnosis. R-CHOP regimen is the standard chemotherapy regimen. Surgical decompression is required in cases of impending neurological injury along with radiotherapy. Primary spinal epidural diffuse large B-cell lymphoma should be considered as a differential diagnosis in patients presenting with back pain and symptoms of impending cauda equina syndrome. It is important to early detect and treat the disease to prevent permanent neurological injury and metastasis.
Identifiants
pubmed: 36389187
doi: 10.1016/j.amsu.2022.104696
pii: S2049-0801(22)01456-X
pmc: PMC9661642
doi:
Types de publication
Case Reports
Langues
eng
Pagination
104696Informations de copyright
© 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
Déclaration de conflit d'intérêts
None.
Références
Acta Radiol. 1992 Jul;33(4):338-42
pubmed: 1633044
World J Oncol. 2015 Oct;6(5):459-463
pubmed: 28983348
Eur J Cancer Clin Oncol. 1989 Aug;25(8):1203-10
pubmed: 2767109
Radiology. 1990 Oct;177(1):209-16
pubmed: 2399318
J Craniovertebr Junction Spine. 2011 Jan;2(1):3-11
pubmed: 22013369
Cancer. 1986 Nov 1;58(9):2120-4
pubmed: 3756827
Neuroradiology. 1996 May;38(4):333-7
pubmed: 8738091
BMC Cancer. 2017 Feb 14;17(1):131
pubmed: 28196505
Mayo Clin Proc. 1996 May;71(5):453-7
pubmed: 8628024
Int J Surg. 2020 Dec;84:226-230
pubmed: 33181358
J Neurol Surg Rep. 2017 Jan;78(1):e1-e4
pubmed: 28180052
Cancer. 1972 Jan;29(1):252-60
pubmed: 5007387
Korean J Spine. 2015 Sep;12(3):177-80
pubmed: 26512278
Crit Rev Oncol Hematol. 2005 Dec;56(3):397-406
pubmed: 16310372
Int J Radiat Oncol Biol Phys. 1986 Feb;12(2):197-202
pubmed: 3949570
Oncol Rep. 2009 Sep;22(3):439-49
pubmed: 19639187
Intern Med. 1992 Apr;31(4):513-5
pubmed: 1633360
Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):817-23
pubmed: 16542791