Systemic Mastocytosis in a Patient with BCR-ABL1-Positive Chronic Myeloid Leukemia in the Remission Phase.


Journal

Case reports in hematology
ISSN: 2090-6560
Titre abrégé: Case Rep Hematol
Pays: United States
ID NLM: 101576456

Informations de publication

Date de publication:
2022
Historique:
received: 06 08 2022
accepted: 25 10 2022
entrez: 17 11 2022
pubmed: 18 11 2022
medline: 18 11 2022
Statut: epublish

Résumé

Systemic mastocytosis (SM) comprises a group of rare disorders resulting from tissue infiltration by pathological mast cells. In a percentage ranging from 5 to 40% in various patient series, SM appears to be associated with an accompanying hematologic neoplasm (SM-AHN). The coexistence of SM with chronic myelogenous leukemia (CML) is extremely rare with only 3 cases in the literature. The natural course of CML has changed dramatically over the past 2 decades with the use of tyrosine kinase inhibitors (TKIs). We report a case of diagnosing SM in a patient in complete molecular remission of CML after stopping TKI treatment.

Identifiants

pubmed: 36389397
doi: 10.1155/2022/7251658
pmc: PMC9649302
doi:

Types de publication

Case Reports

Langues

eng

Pagination

7251658

Informations de copyright

Copyright © 2022 Christos Fokoloros et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

Références

J Allergy Clin Immunol Pract. 2019 Jan;7(1):81-87
pubmed: 30416055
J Allergy Clin Immunol. 2009 Nov;124(5):1047-54
pubmed: 19895993
J Clin Pathol. 2006 Mar;59(3):298-302
pubmed: 16505282
Leuk Res. 2005 Oct;29(10):1227-32
pubmed: 16111540
Blood. 2017 Mar 16;129(11):1420-1427
pubmed: 28031180
Leukemia. 2011 Jun;25(6):1050-3
pubmed: 21445078

Auteurs

Christos Fokoloros (C)

Allergy Unit "D. Kalogeromitros", 2nd Department of Dermatology and Venereology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Periklis Foukas (P)

2nd Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Nikolaos Georgakopoulos (N)

Department of Cytogenetics and Molecular Pathology, Locus Medicus S.A., Athens, Greece.

Zoi Tsakiraki (Z)

2nd Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Anthi Bouchla (A)

Hematology Unit, 2nd Department of Internal Medicine, Propaedeutic, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Vasilliki Pappa (V)

Hematology Unit, 2nd Department of Internal Medicine, Propaedeutic, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Alexandros Katoulis (A)

Allergy Unit "D. Kalogeromitros", 2nd Department of Dermatology and Venereology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Michael Makris (M)

Allergy Unit "D. Kalogeromitros", 2nd Department of Dermatology and Venereology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Sotirios Papageorgiou (S)

Department of Cytogenetics and Molecular Pathology, Locus Medicus S.A., Athens, Greece.

Classifications MeSH