Aedes aegypti Totivirus identified in mosquitoes in the Brazilian Amazon region.
Aedes
Metagenomics
Mosquitoes
Totiviridae
Totivirus
Virome
Journal
Virus genes
ISSN: 1572-994X
Titre abrégé: Virus Genes
Pays: United States
ID NLM: 8803967
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
received:
30
08
2022
accepted:
31
10
2022
pubmed:
18
11
2022
medline:
13
1
2023
entrez:
17
11
2022
Statut:
ppublish
Résumé
The totiviridae family contains viruses with double-stranded RNA genomes of 4.6-7.0 kpb, which encode a capsid protein (CP) and RNA-dependent RNA polymerase (RdRp), and they are approximately 40 nm in diameter with icosahedral symmetry. Totiviruses were first isolated from mosquitoes collected in Shaanxi Province (China). Here, we report a new Aedes aegypti Totivirus (AaTV) identified in mosquitoes from the Amazon rainforest. Mosquitoes (Diptera: Culicidae) were collected from a forest reserve belonging to the Amazon forest in the city of Macapá, Amapá state, Northern Brazil. A viral sequence with a 5748 nucleotide length that was nearly identical to Aedes aegypti Totivirus (AaTV), here named Aedes aegypti Totivirus BR59AP, was detected. A detailed molecular analysis was performed and shows that AaTV-BR59AP is highly related to the AaTV strain from the Caribbean region. We emphasize the importance of the characterization of new viruses in mosquitoes to deepen our understanding of viral diversity in insects and their potential role in disease.
Identifiants
pubmed: 36394716
doi: 10.1007/s11262-022-01955-z
pii: 10.1007/s11262-022-01955-z
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
167-172Subventions
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : CNPq #302677/2019-4
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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