A comparative analysis of telomere length maintenance circuits in fission and budding yeast.
Saccharomyces cerevisiae (Baker’s yeast)
Schizosaccharomyces pombe (fission yeast)
genetic interactions
machine learning model (ML model)
pathways
protein complexes
telomere length maintenance (TLM)
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2022
2022
Historique:
received:
31
08
2022
accepted:
17
10
2022
entrez:
21
11
2022
pubmed:
22
11
2022
medline:
22
11
2022
Statut:
epublish
Résumé
The natural ends of the linear eukaryotic chromosomes are protected by telomeres, which also play an important role in aging and cancer development. Telomere length varies between species, but it is strictly controlled in all organisms. The process of Telomere Length Maintenance (TLM) involves many pathways, protein complexes and interactions that were first discovered in budding and fission yeast model organisms (
Identifiants
pubmed: 36406126
doi: 10.3389/fgene.2022.1033113
pii: 1033113
pmc: PMC9672475
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1033113Informations de copyright
Copyright © 2022 Peretz, Kupiec and Sharan.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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