Preliminary Experience With Quadratus Lumborum Catheters for Postoperative Pain Management in Pediatric-Aged Patients With Contraindications to Epidural Anesthesia.

Children Local anesthetic Pediatric Postoperative analgesia Quadratus lumborum block

Journal

Journal of clinical medicine research
ISSN: 1918-3003
Titre abrégé: J Clin Med Res
Pays: Canada
ID NLM: 101538301

Informations de publication

Date de publication:
Oct 2022
Historique:
received: 17 08 2022
accepted: 23 09 2022
entrez: 21 11 2022
pubmed: 22 11 2022
medline: 22 11 2022
Statut: ppublish

Résumé

Although neuraxial techniques such as caudal and epidural anesthesia were initially the predominant regional anesthetic technique used to provide postoperative analgesia in children, there has been a transition to the use of peripheral nerve blockade such as the quadratus lumborum block (QLB). We present preliminary experience with QL catheters for continuous postoperative analgesia in a cohort of pediatric patients following colorectal surgery. After institutional review board (IRB) approval, we retrospectively reviewed the records of patients who underwent major colorectal surgery and received QL catheters for postoperative analgesia. The postoperative pain control data consisted of QL catheter characteristics, anesthetic agents, adjuncts, pain scores, and opioid consumption during the postoperative period. The study cohort included eight pediatric patients, ranging in age from 1 to 19 years (median age 11.8 years). The QL catheters were placed in the operating room after the induction of anesthesia. Comorbid conditions in the cohort that were contraindications to neuraxial anesthesia included spinal/vertebral malformations, presence of a ventriculoperitoneal (VP) shunt, anal atresia, tracheo-esophageal fistula (VACTERL) association, and coagulation disturbances. All patients underwent complex colorectal or genito-urologic procedures. Bilateral QL catheters were placed in six patients, and unilateral catheters were placed in two patients. Four patients received 0.5% ropivacaine and four patients received 0.2% ropivacaine of an initial bolus. The local anesthetic used for continuous infusion was 0.2% ropivacaine in five patients, 0.1% ropivacaine in two patients, and 1.5% chloroprocaine in one patient, with a median infusion rate of 0.11 mL/kg/h. QL catheter infusions were supplemented with intravenous opioids delivered by patient-controlled or nurse-controlled analgesia. The median opioid requirements in oral morphine milligram equivalents (MME) were 1.2, 1.0, 1.1, 0.5, and 0.6 MME/kg on postoperative days 1 - 5. Daily median pain scores were ≤ 2 during the 5-day postoperative course. All catheters functioned successfully and were in place for a median of 79.3 h. Other than early inadvertent removal of two catheters, no adverse effects were noted. Although our preliminary data suggest the efficacy of QL catheters in providing prolonged postoperative analgesia for up to 3 - 5 days following colorectal procedures, attention needs to be directed at measures to ensure that the catheter is secured to avoid inadvertent removal.

Sections du résumé

Background UNASSIGNED
Although neuraxial techniques such as caudal and epidural anesthesia were initially the predominant regional anesthetic technique used to provide postoperative analgesia in children, there has been a transition to the use of peripheral nerve blockade such as the quadratus lumborum block (QLB). We present preliminary experience with QL catheters for continuous postoperative analgesia in a cohort of pediatric patients following colorectal surgery.
Methods UNASSIGNED
After institutional review board (IRB) approval, we retrospectively reviewed the records of patients who underwent major colorectal surgery and received QL catheters for postoperative analgesia. The postoperative pain control data consisted of QL catheter characteristics, anesthetic agents, adjuncts, pain scores, and opioid consumption during the postoperative period.
Results UNASSIGNED
The study cohort included eight pediatric patients, ranging in age from 1 to 19 years (median age 11.8 years). The QL catheters were placed in the operating room after the induction of anesthesia. Comorbid conditions in the cohort that were contraindications to neuraxial anesthesia included spinal/vertebral malformations, presence of a ventriculoperitoneal (VP) shunt, anal atresia, tracheo-esophageal fistula (VACTERL) association, and coagulation disturbances. All patients underwent complex colorectal or genito-urologic procedures. Bilateral QL catheters were placed in six patients, and unilateral catheters were placed in two patients. Four patients received 0.5% ropivacaine and four patients received 0.2% ropivacaine of an initial bolus. The local anesthetic used for continuous infusion was 0.2% ropivacaine in five patients, 0.1% ropivacaine in two patients, and 1.5% chloroprocaine in one patient, with a median infusion rate of 0.11 mL/kg/h. QL catheter infusions were supplemented with intravenous opioids delivered by patient-controlled or nurse-controlled analgesia. The median opioid requirements in oral morphine milligram equivalents (MME) were 1.2, 1.0, 1.1, 0.5, and 0.6 MME/kg on postoperative days 1 - 5. Daily median pain scores were ≤ 2 during the 5-day postoperative course. All catheters functioned successfully and were in place for a median of 79.3 h. Other than early inadvertent removal of two catheters, no adverse effects were noted.
Conclusions UNASSIGNED
Although our preliminary data suggest the efficacy of QL catheters in providing prolonged postoperative analgesia for up to 3 - 5 days following colorectal procedures, attention needs to be directed at measures to ensure that the catheter is secured to avoid inadvertent removal.

Identifiants

pubmed: 36406942
doi: 10.14740/jocmr4813
pmc: PMC9635806
doi:

Types de publication

Journal Article

Langues

eng

Pagination

425-431

Informations de copyright

Copyright 2022, Pooley et al.

Déclaration de conflit d'intérêts

None to declare.

Références

J Anaesthesiol Clin Pharmacol. 2013 Oct;29(4):550-2
pubmed: 24249997
J Pediatr Surg. 2022 Jul;57(7):1349-1353
pubmed: 35153077
J Anesth. 2016 Jun;30(3):506-9
pubmed: 26984687
Can J Anaesth. 2018 Feb;65(2):178-187
pubmed: 29164530
Eur J Anaesthesiol. 2017 Sep;34(9):587-595
pubmed: 28731927
N Engl J Med. 2002 Oct 3;347(14):1094-103
pubmed: 12362012
Clin J Pain. 2003 Sep-Oct;19(5):286-97
pubmed: 12966254
Br J Anaesth. 2015 Sep;115(3):457-62
pubmed: 26205902
Anesth Analg. 2017 Jul;125(1):303-312
pubmed: 28277325
A A Case Rep. 2015 Oct 1;5(7):107-11
pubmed: 26402020
Anaesthesia. 2021 Jan;76 Suppl 1:74-88
pubmed: 33426659
Anesthesiology. 2019 Feb;130(2):322-335
pubmed: 30688787
J Pain Res. 2016 Nov 18;9:1067-1072
pubmed: 27920572
Anesth Analg. 2011 Oct;113(4):904-25
pubmed: 21821511
A A Case Rep. 2017 Jan 1;8(1):4-6
pubmed: 28036319
J Clin Anesth. 2016 Dec;35:235-237
pubmed: 27871532
Anesth Analg. 2007 Nov;105(5):1234-42, table of contents
pubmed: 17959949
Anesth Analg. 2000 Jul;91(1):16-26
pubmed: 10866880
A A Case Rep. 2015 Feb 1;4(3):34-6
pubmed: 25642956
Anesth Analg. 2012 Dec;115(6):1353-64
pubmed: 22696610
A A Case Rep. 2016 Sep 15;7(6):129-31
pubmed: 27513972
Paediatr Anaesth. 2013 Oct;23(10):959-61
pubmed: 23927552
Paediatr Anaesth. 2017 Mar;27(3):300-304
pubmed: 28098413
Anesth Analg. 2003 Aug;97(2):534-540
pubmed: 12873949
J Surg Res. 2021 Mar;259:230-241
pubmed: 33051063
Pain Res Manag. 2008 Jan-Feb;13(1):25-32
pubmed: 18301813
Anaesthesia. 2017 Jan;72(1):73-79
pubmed: 27730633

Auteurs

Rachel Pooley (R)

Heritage College of Osteopathic Medicine, Dublin Campus, Dublin, Ohio and Ohio University, Athens, OH, USA.

Giorgio Veneziano (G)

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.

Candice Burrier (C)

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.

Nguyen K Tram (NK)

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.

Joseph D Tobias (JD)

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.

Classifications MeSH