Doxycycline Induced Pancreatitis: An Uncommon Complication of a Common Drug.

DIAP DIP adverse drug reaction doxycycline drug induced acute pancreatitis

Journal

Pharmacy (Basel, Switzerland)
ISSN: 2226-4787
Titre abrégé: Pharmacy (Basel)
Pays: Switzerland
ID NLM: 101678532

Informations de publication

Date de publication:
30 Oct 2022
Historique:
received: 27 09 2022
revised: 27 10 2022
accepted: 29 10 2022
entrez: 22 11 2022
pubmed: 23 11 2022
medline: 23 11 2022
Statut: epublish

Résumé

We describe the risk factors for the development, timing, and severity of doxycycline induced acute pancreatitis (DIAP) in two case reports and a review of prior published cases, to better understand DIAP. Clinicians must maintain a high level of suspicion for DIAP in patients presenting with acute pancreatitis, while on doxycycline therapy. The latency and severity of DIAP are variable, making diagnosis challenging. Treatment includes bowel rest, hydration, and discontinuation of doxycycline.

Identifiants

pubmed: 36412820
pii: pharmacy10060144
doi: 10.3390/pharmacy10060144
pmc: PMC9680210
pii:
doi:

Types de publication

Case Reports

Langues

eng

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Auteurs

William Reiche (W)

Department of Medicine, CHI Health Creighton University Medical Center, Omaha, NE 68124, USA.

Faith Abodunrin (F)

Department of Medicine, CHI Health Creighton University Medical Center, Omaha, NE 68124, USA.

Chris Destache (C)

Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, NE 68178, USA.

Rajani Rangray (R)

Division of Gastroenterology and Hepatology, CHI Creighton University Medical Center, Omaha, NE 68124, USA.

Manasa Velagapudi (M)

Division of Infectious Diseases, CHI Creighton University Medical Center, Omaha, NE 68124, USA.

Classifications MeSH