On Deterministic and Stochastic Multiple Pathogen Epidemic Models.
epidemic models
finite element method
persistence time
stochastic differential equation
Journal
Epidemiologia (Basel, Switzerland)
ISSN: 2673-3986
Titre abrégé: Epidemiologia (Basel)
Pays: Switzerland
ID NLM: 9918333886406676
Informations de publication
Date de publication:
12 Aug 2021
12 Aug 2021
Historique:
received:
02
06
2021
revised:
04
08
2021
accepted:
05
08
2021
entrez:
23
11
2022
pubmed:
12
8
2021
medline:
12
8
2021
Statut:
epublish
Résumé
In this paper, we consider a stochastic epidemic model with two pathogens. In order to analyze the coexistence of two pathogens, we compute numerically the expectation time until extinction (the mean persistence time), which satisfies a stationary partial differential equation with degenerate variable coefficients, related to backward Kolmogorov equation. I use the finite element method in order to solve this equation, and we implement it in FreeFem++. The main conclusion of this paper is that the deterministic and stochastic epidemic models differ considerably in predicting coexistence of the two diseases and in the extinction outcome of one of them. Now, the main challenge would be to find an explanation for this result.
Identifiants
pubmed: 36417229
pii: epidemiologia2030025
doi: 10.3390/epidemiologia2030025
pmc: PMC9620904
doi:
Types de publication
Journal Article
Langues
eng
Pagination
325-337Subventions
Organisme : Ministerio de Ciencia Tecnología y Telecomunicaciones
ID : PGC2018-094522-B-100
Organisme : Eusko Jaurlaritza
ID : IT1247-19
Références
Bull Math Biol. 2004 Jul;66(4):841-64
pubmed: 15210322