The role of ion channels in immune-related diseases.
Autoimmune diseases
Immune deficiency diseases
Ion channels
Major organs
Transporter
Journal
Progress in biophysics and molecular biology
ISSN: 1873-1732
Titre abrégé: Prog Biophys Mol Biol
Pays: England
ID NLM: 0401233
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
received:
07
09
2022
revised:
26
10
2022
accepted:
10
11
2022
pubmed:
24
11
2022
medline:
7
2
2023
entrez:
23
11
2022
Statut:
ppublish
Résumé
Ion channel is an integral membrane protein that allows the permeation of charge ions across hydrophobic phospholipid membranes, including plasma membranes and organelle membranes (such as mitochondria, endoplasmic reticulum and vacuoles), which are widely distributed in various cells and tissues, such as cardiomyocytes, smooth muscle cells, and nerve cells. Ion channels establish membrane potential by regulating ion concentration and membrane potential. Membrane potential plays an important role in cells. Studies have shown that ion channels play a role in a number of immune-related diseases caused by functional defects in ion channels on immune or non-immune cells in major human organs, usually affecting specific organs or multiple organs. The present review discusses the relationship between ion channels and immune diseases in major organs of the human body.
Identifiants
pubmed: 36417963
pii: S0079-6107(22)00119-5
doi: 10.1016/j.pbiomolbio.2022.11.003
pii:
doi:
Substances chimiques
Ion Channels
0
Ions
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
129-140Informations de copyright
Copyright © 2022 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.