RNA with chemotherapeutic base analogues as a dual-functional anti-cancer drug.
5FU
Chemotherapy
RNA
immunotherapy
toll like receptor
type I interferon
Journal
Oncoimmunology
ISSN: 2162-402X
Titre abrégé: Oncoimmunology
Pays: United States
ID NLM: 101570526
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
24
11
2022
pubmed:
25
11
2022
medline:
26
11
2022
Statut:
epublish
Résumé
Nanoparticles of different sizes formulated with unmodified RNA and Protamine differentially engage Toll-like Receptors (TLRs) and activate innate immune responses
Identifiants
pubmed: 36419823
doi: 10.1080/2162402X.2022.2147665
pii: 2147665
pmc: PMC9677980
doi:
Substances chimiques
RNA
63231-63-0
Antineoplastic Agents
0
Protamines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2147665Informations de copyright
© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.
Déclaration de conflit d'intérêts
Steve Pascolo is the inventor on a patent “US10980875B2 Cytotoxic immunostimulating particles and uses thereof”. The other authors report there are no competing interests to declare.
Références
Hum Vaccin Immunother. 2013 Oct;9(10):2263-76
pubmed: 23921513
Methods Mol Biol. 2017;1499:155-163
pubmed: 27987148
J Immunol. 2009 Aug 1;183(3):1569-76
pubmed: 19587008
Prostate. 2009 Jun 15;69(9):917-27
pubmed: 19267352
Drug Deliv. 2020 Dec;27(1):1231-1235
pubmed: 32804028
Pharmaceutics. 2021 Jun 14;13(6):
pubmed: 34198550
Nat Med. 2005 Feb;11(2):138-45
pubmed: 15654326
Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2764-9
pubmed: 19188597
Eur J Immunol. 2004 Feb;34(2):537-47
pubmed: 14768059
Handb Exp Pharmacol. 2008;(183):221-35
pubmed: 18071662
Chimia (Aarau). 2019 May 29;73(6):391-394
pubmed: 31118121
Eur J Immunol. 2006 Oct;36(10):2807-16
pubmed: 17013976
Blood. 2010 Jun 3;115(22):4533-41
pubmed: 20304804
J Immunother. 2011 Jan;34(1):1-15
pubmed: 21150709
Nat Rev Drug Discov. 2018 Oct;17(10):751-767
pubmed: 30190565
Clin Cancer Res. 2018 Feb 15;24(4):882-895
pubmed: 29162646
Cancer Res. 2011 Aug 1;71(15):5123-33
pubmed: 21697281
J Immunother Cancer. 2015 Jun 16;3:26
pubmed: 26082837
Eur J Immunol. 2005 May;35(5):1557-66
pubmed: 15832293
Nano Lett. 2017 Mar 8;17(3):1326-1335
pubmed: 28273716
Nat Rev Cancer. 2003 May;3(5):330-8
pubmed: 12724731