Autopsy Case Report of Severe COVID-19 Pneumonia at a General Municipal Hospital.


Journal

The Tokai journal of experimental and clinical medicine
ISSN: 2185-2243
Titre abrégé: Tokai J Exp Clin Med
Pays: Japan
ID NLM: 7704186

Informations de publication

Date de publication:
20 Dec 2022
Historique:
received: 19 01 2022
accepted: 13 07 2022
entrez: 24 11 2022
pubmed: 25 11 2022
medline: 26 11 2022
Statut: epublish

Résumé

We present the autopsy procedure and findings of severe coronavirus disease 2019 (COVID-19) pneumonia in an 85-year-old man. The patient required intubation immediately after admission for severe COVID-19 pneumonia. He had severe hypoxia that did not improve despite treatment with remdesivir, corticosteroids, and appropriate mechanical ventilation. On day 13, the patient developed sudden hypercapnia. His renal dysfunction subsequently worsened and became associated with hyperkalemia, and he passed away on day 15. An autopsy was performed to clarify the cause of the hypercapnic hypoxia. None of the medical personnel involved in the autopsy developed symptoms of COVID-19. Histologic examination showed various stages of diffuse alveolar damage throughout the lungs, with intra-alveolar hemorrhage in the upper zones. Microscopic examination of the kidneys revealed acute tubular necrosis. There was no significant systemic thrombosis. The autopsy findings were consistent with those typical of COVID-19.

Identifiants

pubmed: 36420546

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

162-164

Auteurs

Takashi Naruke (T)

Department of Cardiovascular Medicine, Odawara Municipal Hospital, 46 Kuno, Odawara, Kanagawa 250-8558, Japan. takanalu@kitasato-u.ac.jp.

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Classifications MeSH