Commercially Available Enteric Empty Hard Capsules, Production Technology and Application.
ECDDT technology
acid resistance
commercial capsules
encapsulation
enteric administration
hard capsules
Journal
Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453
Informations de publication
Date de publication:
13 Nov 2022
13 Nov 2022
Historique:
received:
27
10
2022
revised:
09
11
2022
accepted:
11
11
2022
entrez:
24
11
2022
pubmed:
25
11
2022
medline:
25
11
2022
Statut:
epublish
Résumé
Currently, there is a growing need to prepare small batches of enteric capsules for individual therapy or clinical evaluation since many acidic-sensitive substances should be protected from the stomach's acidic environment, including probiotics or fecal material, in the fecal microbiota transplantation (FMT) process. A suitable method seems to be the encapsulation of drugs or lyophilized alternatively frozen biological suspensions in commercial hard enteric capsules prepared by so-called Enteric Capsule Drug Delivery Technology (ECDDT). Manufacturers supply these types of capsules, made from pH-soluble polymers, in products such as AR Caps
Identifiants
pubmed: 36422528
pii: ph15111398
doi: 10.3390/ph15111398
pmc: PMC9696354
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Masaryk University
ID : MUNI/IGA/0942/2021
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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