Survivin promotes a glycolytic switch in CD4

Biological sciences Immunology Transcriptomics

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
22 Dec 2022
Historique:
received: 22 07 2022
revised: 10 08 2022
accepted: 04 11 2022
entrez: 25 11 2022
pubmed: 26 11 2022
medline: 26 11 2022
Statut: epublish

Résumé

In this study, we explore the role of nuclear survivin in maintaining the effector phenotype of IFNγ-producing T cells acting through the transcriptional control of glucose utilization. High expression of survivin in CD4

Identifiants

pubmed: 36425763
doi: 10.1016/j.isci.2022.105526
pii: S2589-0042(22)01798-9
pmc: PMC9678772
doi:

Types de publication

Journal Article

Langues

eng

Pagination

105526

Informations de copyright

© 2022 The Authors.

Déclaration de conflit d'intérêts

The authors declare no competing interests.

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Auteurs

Malin C Erlandsson (MC)

Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 40530 Gothenburg, Sweden.
Rheumatology Clinic, Sahlgrenska University Hospital, Gröna stråket 16, 41346 Gothenburg, Sweden.

Karin M E Andersson (KME)

Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 40530 Gothenburg, Sweden.

Nina Y Oparina (NY)

Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 40530 Gothenburg, Sweden.

Venkataragavan Chandrasekaran (V)

Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 40530 Gothenburg, Sweden.

Tibor Saghy (T)

Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 40530 Gothenburg, Sweden.

Anastasios Damdimopoulos (A)

Bioinformatics and Expression Analysis Core Facility, Department of Biosciences and Nutrition, Karolinska Institute, 141 41 Huddinge, Sweden.

Maria-Jose Garcia-Bonete (MJ)

Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, 40530 Gothenburg, Sweden.

Zakaria Einbeigi (Z)

Department of Medicine and Oncology, Southern Älvsborg Hospital, 50182 Borås, Sweden.
Department of Oncology, Institute of Clinical Science at Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden.

Sofia T Silfverswärd (ST)

Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 40530 Gothenburg, Sweden.

Marcela Pekna (M)

Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, University of Gothenburg, Box 440, 40530 Gothenburg, Sweden.

Gergely Katona (G)

Department of Chemistry and Molecular Biology, Faculty of Science, University of Gothenburg, 405 30 Gothenburg, Sweden.

Maria I Bokarewa (MI)

Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 40530 Gothenburg, Sweden.
Rheumatology Clinic, Sahlgrenska University Hospital, Gröna stråket 16, 41346 Gothenburg, Sweden.

Classifications MeSH