Pleural and mediastinal effusions after the extracardiac total cavopulmonary connection: Risk factors and impact on outcome.

congenital heart disease outcome pleural effusion total cavopulmonary connection (TCPC) univentricular heart

Journal

Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388

Informations de publication

Date de publication:
2022
Historique:
received: 23 08 2022
accepted: 17 10 2022
entrez: 25 11 2022
pubmed: 26 11 2022
medline: 26 11 2022
Statut: epublish

Résumé

This study investigated the volume and duration of pleural and mediastinal effusions following extracardiac total cavopulmonary connection, as well as preoperative risk factors and their impact on outcome. A total of 210 patients who underwent extracardiac total cavopulmonary connection at our center between 2012 and 2020 were included in this study. Postoperative daily amount of pleural and mediastinal drainage were collected and factors influencing duration and amount of effusions were analyzed. The impact of effusions on adverse events was analyzed. Median age at extracardiac total cavopulmonary connection was 2.2 (interquartile range, 1.8-2.7) years with median weight of 11.6 (10.7-13.0) kg. Overall duration of drainage after extracardiac total cavopulmonary connection was 9 (6-17) days. The total volume of mediastinal, right pleural, and left pleural drainage was 18.8 (11.9-36.7), 64.4 (27.4-125.9), and 13.6 (0.0-53.5) mL/kg, respectively. Hypoplastic left heart syndrome ( Volume and duration of pleural and mediastinal effusions following extracardiac total cavopulmonary connection were related with hypoplastic left heart syndrome, aortopulmonary collaterals, and end-diastolic pressure. The duration of drainage for effusions was a risk factor for adverse events after total cavopulmonary connection.

Sections du résumé

Background UNASSIGNED
This study investigated the volume and duration of pleural and mediastinal effusions following extracardiac total cavopulmonary connection, as well as preoperative risk factors and their impact on outcome.
Materials and methods UNASSIGNED
A total of 210 patients who underwent extracardiac total cavopulmonary connection at our center between 2012 and 2020 were included in this study. Postoperative daily amount of pleural and mediastinal drainage were collected and factors influencing duration and amount of effusions were analyzed. The impact of effusions on adverse events was analyzed.
Results UNASSIGNED
Median age at extracardiac total cavopulmonary connection was 2.2 (interquartile range, 1.8-2.7) years with median weight of 11.6 (10.7-13.0) kg. Overall duration of drainage after extracardiac total cavopulmonary connection was 9 (6-17) days. The total volume of mediastinal, right pleural, and left pleural drainage was 18.8 (11.9-36.7), 64.4 (27.4-125.9), and 13.6 (0.0-53.5) mL/kg, respectively. Hypoplastic left heart syndrome (
Conclusion UNASSIGNED
Volume and duration of pleural and mediastinal effusions following extracardiac total cavopulmonary connection were related with hypoplastic left heart syndrome, aortopulmonary collaterals, and end-diastolic pressure. The duration of drainage for effusions was a risk factor for adverse events after total cavopulmonary connection.

Identifiants

pubmed: 36426216
doi: 10.3389/fcvm.2022.1026445
pmc: PMC9678908
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1026445

Informations de copyright

Copyright © 2022 Heinisch, Metz, Staehler, Mayr, Vodiskar, Strbad, Ruf, Ewert, Hager, Hörer and Ono.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Circulation. 2006 Jul 4;114(1 Suppl):I56-61
pubmed: 16820638
Eur J Cardiothorac Surg. 2017 May 1;51(5):995-1002
pubmed: 28329109
J Thorac Dis. 2016 Jan;8(1):43-51
pubmed: 26904211
Eur J Cardiothorac Surg. 2022 Feb 18;61(3):497-504
pubmed: 34355744
J Thorac Cardiovasc Surg. 2019 May;157(5):2005-2013.e3
pubmed: 30578061
J Thorac Cardiovasc Surg. 2004 Jun;127(6):1664-9
pubmed: 15173721
J Thorac Cardiovasc Surg. 2012 Dec;144(6):1329-36
pubmed: 22502974
Ann Thorac Surg. 2015 Jan;99(1):148-55
pubmed: 25442983
Am J Cardiol. 2017 Jun 1;119(11):1866-1871
pubmed: 28385177
J Card Surg. 2020 Oct;35(10):2688-2694
pubmed: 32720367
J Thorac Cardiovasc Surg. 2010 Jul;140(1):129-36
pubmed: 20620378
J Am Coll Cardiol. 2020 Jul 28;76(4):419-431
pubmed: 32703513
J Am Coll Cardiol. 2011 Jun 14;57(24):2437-43
pubmed: 21658565
Ann Thorac Surg. 2007 Sep;84(3):894-9
pubmed: 17720396
Int J Cardiol Heart Vasc. 2021 Jul 07;35:100825
pubmed: 34286062
J Thorac Cardiovasc Surg. 2015 Sep;150(3):481-7
pubmed: 26254747
J Thorac Cardiovasc Surg. 2018 May;155(5):2069-2077
pubmed: 29249497
Ann Thorac Surg. 1997 Jul;64(1):37-42; discussion 43
pubmed: 9236332
Pediatr Cardiol. 2019 Dec;40(8):1545-1552
pubmed: 31435694
Circulation. 2002 Jan 15;105(2):207-12
pubmed: 11790702
J Am Coll Cardiol. 2006 May 16;47(10):2065-73
pubmed: 16697327
Eur J Cardiothorac Surg. 2015 Dec;48(6):825-32; discussion 832
pubmed: 25769469
Ann Thorac Surg. 2008 Aug;86(2):576-81; discussion 581-2
pubmed: 18640336
Int J Cardiol. 2022 Oct 1;364:38-43
pubmed: 35714716
J Thorac Cardiovasc Surg. 2014 Aug;148(2):566-75
pubmed: 24280718
Eur J Cardiothorac Surg. 2016 Oct;50(4):632-641
pubmed: 27009106
Interact Cardiovasc Thorac Surg. 2019 Jul 1;29(1):85-92
pubmed: 31220277
Pediatr Cardiol. 2015 Dec;36(8):1680-4
pubmed: 26104382
Front Pediatr. 2019 Nov 07;7:456
pubmed: 31788459
Pediatr Cardiol. 2021 Jan;42(1):89-99
pubmed: 32970244
J Thorac Cardiovasc Surg. 2012 Sep;144(3):547-52
pubmed: 22743174
Heart. 2012 Jun;98(12):934-40
pubmed: 22626901
J Am Heart Assoc. 2022 Jun 7;11(11):e026087
pubmed: 35621213
J Thorac Cardiovasc Surg. 2008 Jul;136(1):108-16
pubmed: 18603062
Circulation. 2001 Sep 18;104(12 Suppl 1):I148-51
pubmed: 11568047
Ann Thorac Surg. 2019 Nov;108(5):1439-1446
pubmed: 31279788
Cardiol Young. 2001 Mar;11(2):161-8
pubmed: 11293733

Auteurs

Paul Philipp Heinisch (PP)

Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Division of Congenital and Pediatric Heart Surgery, University Hospital of Munich, Ludwig-Maximilians-Universität, Munich, Germany.

Paul Metz (P)

Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Division of Congenital and Pediatric Heart Surgery, University Hospital of Munich, Ludwig-Maximilians-Universität, Munich, Germany.

Helena Staehler (H)

Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Division of Congenital and Pediatric Heart Surgery, University Hospital of Munich, Ludwig-Maximilians-Universität, Munich, Germany.

Benedikt Mayr (B)

Department of Cardiovascular Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.

Janez Vodiskar (J)

Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Division of Congenital and Pediatric Heart Surgery, University Hospital of Munich, Ludwig-Maximilians-Universität, Munich, Germany.

Martina Strbad (M)

Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Division of Congenital and Pediatric Heart Surgery, University Hospital of Munich, Ludwig-Maximilians-Universität, Munich, Germany.

Bettina Ruf (B)

Department of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Technische Universität München, Munich, Germany.

Peter Ewert (P)

Department of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Technische Universität München, Munich, Germany.

Alfred Hager (A)

Department of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Technische Universität München, Munich, Germany.

Jürgen Hörer (J)

Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Division of Congenital and Pediatric Heart Surgery, University Hospital of Munich, Ludwig-Maximilians-Universität, Munich, Germany.

Masamichi Ono (M)

Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Division of Congenital and Pediatric Heart Surgery, University Hospital of Munich, Ludwig-Maximilians-Universität, Munich, Germany.

Classifications MeSH