Toward comprehensive value assessment for Alzheimer's disease innovations.
Alzheimer's disease
deliberative appraisal
elements of value
evidence dashboards
health technology assessment
multi-criteria decision analysis
patient-caregiver perspective
value analytics
value assessment
value framework
value measures
Journal
Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978
Informations de publication
Date de publication:
04 2023
04 2023
Historique:
revised:
10
10
2022
received:
10
05
2022
accepted:
17
10
2022
medline:
17
4
2023
pubmed:
26
11
2022
entrez:
25
11
2022
Statut:
ppublish
Résumé
Assessing medical technologies for Alzheimer's disease (AD) creates challenges for current methods of value assessment. New value assessment approaches for AD are also needed. We adapted concepts from health economics to help guide decision makers to more informed decisions about AD therapies and diagnostics. We propose a value framework based on five categories: perspective, value elements, analysis, reporting, and decision making. AD value assessments should include the perspective of the patient-caregiver dyad. We propose a broader array of value elements than currently used. Analytics and decision methods can synthesize evidence for all elements of value. Decisions should use a "deliberative appraisal" approach informed by the composite evidence and be transparently reported. Using the proposed framework, the value of forthcoming innovations for AD may be more thoroughly assessed for and by all stakeholders. It can guide decision makers to carefully consider all relevant elements of value contributing to more holistic and transparent decision making. Alzheimer's disease challenges common methods of evaluating medical technology. Using current methods, new AD innovations might not be appropriately valued. Poor value assessments will adversely affect patient access to AD innovations. A full AD value framework expands perspective, elements, analysis, decision-making, reporting.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1558-1567Informations de copyright
© 2022 Eli Lilly and Company and The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
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