Angiotensin II Modulates Calcium/Phosphate Excretion in Experimental Model of Hypertension: Focus on Bone.
angiotensin II
bone
experimental hypertension
rats
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
14 Nov 2022
14 Nov 2022
Historique:
received:
02
10
2022
revised:
04
11
2022
accepted:
08
11
2022
entrez:
26
11
2022
pubmed:
27
11
2022
medline:
27
11
2022
Statut:
epublish
Résumé
A link between hypertension and long-term bone health has been suggested. The aim of this study was to investigate the effects of chronic angiotensin II administration on urinary calcium/phosphate excretion, bone mineral density, bone remodeling and osteoblast population in a well-established experimental model of hypertension, in the absence of possible confounding factors that could affect bone metabolism. Male Sprague-Dawley rats, divided in the following groups: (a) Angiotensin II (Ang II, 200 ng/kg/min, osmotic minipumps, sub cutis,
Identifiants
pubmed: 36428495
pii: biomedicines10112928
doi: 10.3390/biomedicines10112928
pmc: PMC9687632
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Universita' Milano Bicocca. Fondo Ateneo Ricerca (G.Za)
ID : FAR G.Za 2020
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