Biological Effects and Toxicity of Compounds Based on Cured Epoxy Resins.

biological effect cytotoxic effect epoxides metallic fillers resin-based composites

Journal

Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357

Informations de publication

Date de publication:
14 Nov 2022
Historique:
received: 28 09 2022
revised: 04 11 2022
accepted: 10 11 2022
entrez: 26 11 2022
pubmed: 27 11 2022
medline: 27 11 2022
Statut: epublish

Résumé

The aim of this work was to investigate selected biological and toxicity properties of cured epoxy resin-based compounds based on a bisphenol A epoxy resin, cold-cured by a polyamide and containing two types of metal powders (aluminum and copper). This study involved cytotoxicity analysis, pH measurements, absorbance measurements and sterilization. The cytotoxicity analysis was conducted to determine the harmful degree of the cured epoxy resin. Aimed at identifying toxic agents in cured compounds, the cytotoxicity analysis involved absorbance measurements in an entire wavelength range. Cytotoxicity and absorbance results demonstrated that the extracts of all the tested resin samples had no cytotoxic effects on the cells of living organisms. The absorbance values obtained over the entire wavelength range did not point to the formation of aggregations, which proved that no toxic agents harmful to living organisms were extracted from the resin samples. Based on the results obtained, it can be concluded that all tested compounds, based on epoxy resins, which are also used as adhesives in various applications, are essentially safe materials when using such formulations in a cured state.

Identifiants

pubmed: 36433042
pii: polym14224915
doi: 10.3390/polym14224915
pmc: PMC9698122
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Anna Rudawska (A)

Faculty of Mechanical Engineering, Lublin University of Technology, Nadbystrzycka 36 St., 20-618 Lublin, Poland.

Katarzyna Sarna-Boś (K)

Department of Dental Prosthetics, Medical University of Lublin, Chodźki 6, 20-093 Lublin, Poland.

Adrianna Rudawska (A)

Department of Pharmacology and Toxicology, National Veterinary Research Institute, Aleja Partyzantów 57, 24-100 Puławy, Poland.

Ewa Olewnik-Kruszkowska (E)

Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7 St., 87-200 Toruń, Poland.

Mariaenrica Frigione (M)

Department of Innovation Engineering, University of Salento, Via Arnesano, 73100 Lecce, Italy.

Classifications MeSH