The first report of a known 4A syndrome patient with suspected manifestations of COVID-19, what was the final outcome?

4A syndrome Achalasia Addison’s disease Alacrima COVID-19

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
Dec 2022
Historique:
received: 20 05 2022
revised: 01 09 2022
accepted: 14 11 2022
pubmed: 29 11 2022
medline: 29 11 2022
entrez: 28 11 2022
Statut: ppublish

Résumé

The present study was performed on a 24-year-old Iranian man referred to Hospital with suspected symptoms of COVID-19, including fever, weakness, and cough. According to medical history, he had Alacrima, esophageal Achalasia, and adrenal insufficiency from childhood. Based on medical records and clinical examinations, the physician suspected 3A syndrome in the patient and requested further examination for MRI, CXR, and COVID-19 RT-PCR test. The result of the COVID-19 RT-PCR test was negative the next day. The patient's CXR showed ground-glass opacity (GGO) and pulmonary fibrosis. Based on images and MRI reports, severe posterior cortical atrophy disproportionate to chronological age and bilateral atrophy of the lacrimal gland were reported. After reviewing and summarizing the records, history, examinations, and Paraclinical tests, the patient was identified as a case of 4A syndrome.

Identifiants

pubmed: 36440457
doi: 10.1016/j.heliyon.2022.e11766
pii: S2405-8440(22)03054-7
pmc: PMC9675088
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e11766

Informations de copyright

© 2022 The Authors.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

Indian J Pediatr. 2007 Oct;74(10):959-61
pubmed: 17978460
J Indian Soc Pedod Prev Dent. 2018 Apr-Jun;36(2):125-129
pubmed: 29970628
Can J Ophthalmol. 2005 Aug;40(4):502-5
pubmed: 16116518
J Pediatr Endocrinol Metab. 1999 Apr;12 Suppl 1:277-93
pubmed: 10698592
Clin Radiol. 1991 Oct;44(4):260-4
pubmed: 1659963
Eur J Pediatr. 2012 Oct;171(10):1453-9
pubmed: 22538409
J Pediatr. 1996 Jul;129(1):156-9
pubmed: 8757578
J Neurol Neurosurg Psychiatry. 2003 May;74(5):654-7
pubmed: 12700313
Am J Case Rep. 2016 Oct 04;17:703-706
pubmed: 27698338
Exp Ther Med. 2015 Oct;10(4):1277-1282
pubmed: 26622478
Eur J Pediatr. 1995 Mar;154(3):191-6
pubmed: 7758515
Iran J Pediatr. 2010 Mar;20(1):101-6
pubmed: 23056690
Osteoporos Int. 2016 Feb;27(2):521-6
pubmed: 26243364
Singapore Med J. 2012 May;53(5):e92-4
pubmed: 22584989
Eur J Pediatr. 1995 Jan;154(1):18-23
pubmed: 7895750
BMC Pediatr. 2018 Jan 15;18(1):6
pubmed: 29334914
Endocrinology. 2013 Sep;154(9):3209-18
pubmed: 23825130
Gastroenterol Hepatol Bed Bench. 2012 Spring;5(2):112-5
pubmed: 24834210
Endocr J. 1999 Feb;46(1):227-30
pubmed: 10426592
Lancet. 1978 Jun 17;1(8077):1284-6
pubmed: 78049
Pediatric Health Med Ther. 2019 Aug 29;10:99-106
pubmed: 31695556
Clin Genet. 2005 Sep;68(3):215-21
pubmed: 16098009
Eur J Pediatr. 2010 Nov;169(11):1323-8
pubmed: 20499090
Hum Mol Genet. 2001 Feb 1;10(3):283-90
pubmed: 11159947

Auteurs

Elham Azmoodeh (E)

School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.

Amirhessam Kheirieh (A)

School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.

Sepideh Mahdavi (S)

Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.

Fatemeh Toufan (F)

Department of Internal Medicine, Clinical Research Development Unit, Bahar Hospital, Shahroud University of Medical Sciences, Shahroud, Iran.

Sepideh Nazemi (S)

Department of Internal Medicine, Clinical Research Development Unit, Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran.

Classifications MeSH