Delays in Presentation After Traumatic Spinal Cord Injury-A Systematic Review.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
01 2023
Historique:
received: 12 09 2022
accepted: 20 10 2022
pubmed: 29 11 2022
medline: 4 1 2023
entrez: 28 11 2022
Statut: ppublish

Résumé

Prompt surgical decompression after traumatic spinal cord injury (TSCI) may be associated with improved sensorimotor outcomes. Delays in presentation may prevent timely decompression after TSCI. To systematically review existing studies investigating delays in presentation after TSCI in low- and middle-income countries (LMICs) and high-income countries (HICs). A systematic review was conducted and studies featuring quantitative or qualitative data on prehospital delays in TSCI presentation were included. Studies lacking quantitative or qualitative data on prehospital delays in TSCI presentation, case reports or series with <5 patients, review articles, or animal studies were excluded from our analysis. After exclusion criteria were applied, 24 studies were retained, most of which were retrospective. Eleven studies were from LMICs and 13 were from HICs. Patients with TSCI in LMICs were younger than those in HICs, and most patients were male in both groups. A greater proportion of patients with TSCI in studies from LMICs presented >24 hours after injury (HIC average proportion, 12.0%; LMIC average proportion, 49.9%; P = 0.01). Financial barriers, lack of patient awareness and education, and prehospital transportation barriers were more often cited as reasons for delays in LMICs than in HICs, with prehospital transportation barriers cited as a reason for delay by every LMIC study included in this review. Disparities in prehospital infrastructure between HICs and LMICs subject more patients in LMICs to increased delays in presentation to care.

Sections du résumé

BACKGROUND
Prompt surgical decompression after traumatic spinal cord injury (TSCI) may be associated with improved sensorimotor outcomes. Delays in presentation may prevent timely decompression after TSCI.
OBJECTIVE
To systematically review existing studies investigating delays in presentation after TSCI in low- and middle-income countries (LMICs) and high-income countries (HICs).
METHODS
A systematic review was conducted and studies featuring quantitative or qualitative data on prehospital delays in TSCI presentation were included. Studies lacking quantitative or qualitative data on prehospital delays in TSCI presentation, case reports or series with <5 patients, review articles, or animal studies were excluded from our analysis.
RESULTS
After exclusion criteria were applied, 24 studies were retained, most of which were retrospective. Eleven studies were from LMICs and 13 were from HICs. Patients with TSCI in LMICs were younger than those in HICs, and most patients were male in both groups. A greater proportion of patients with TSCI in studies from LMICs presented >24 hours after injury (HIC average proportion, 12.0%; LMIC average proportion, 49.9%; P = 0.01). Financial barriers, lack of patient awareness and education, and prehospital transportation barriers were more often cited as reasons for delays in LMICs than in HICs, with prehospital transportation barriers cited as a reason for delay by every LMIC study included in this review.
CONCLUSIONS
Disparities in prehospital infrastructure between HICs and LMICs subject more patients in LMICs to increased delays in presentation to care.

Identifiants

pubmed: 36441093
pii: S1878-8750(22)01492-9
doi: 10.1016/j.wneu.2022.10.086
pii:
doi:

Types de publication

Systematic Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e121-e130

Informations de copyright

Copyright © 2022. Published by Elsevier Inc.

Auteurs

Tej D Azad (TD)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Sumil K Nair (SK)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Anita L Kalluri (AL)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Joshua Materi (J)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

A Karim Ahmed (AK)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Jawad Khalifeh (J)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Nancy Abu-Bonsrah (N)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA; Research Department, Association of Future African Neurosurgeons, Yaounde, Cameroon.

Lisa N Sharwood (LN)

John Walsh Centre for Rehabilitation Research, Kolling Institute, Sydney Medical School-Northern, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

Robert C Sterner (RC)

Department of Neurological Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Nathaniel P Brooks (NP)

Department of Neurological Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Safwan Alomari (S)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Farah N Musharbash (FN)

Department of Orthopedic Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Kevin Mo (K)

Department of Orthopedic Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Daniel Lubelski (D)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Timothy F Witham (TF)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Nicholas Theodore (N)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Ali Bydon (A)

Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA. Electronic address: abydon1@jhmi.edu.

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Classifications MeSH