Evaluation of a pilot emergency department linkage to care program for patients previously diagnosed with Hepatitis C.


Journal

Journal of viral hepatitis
ISSN: 1365-2893
Titre abrégé: J Viral Hepat
Pays: England
ID NLM: 9435672

Informations de publication

Date de publication:
02 2023
Historique:
revised: 11 11 2022
received: 05 09 2022
accepted: 16 11 2022
pmc-release: 01 02 2024
pubmed: 29 11 2022
medline: 20 1 2023
entrez: 28 11 2022
Statut: ppublish

Résumé

There is a significant number of Emergency Department (ED) patients with known chronic hepatitis C virus (HCV) infection who have not been treated with directly acting antivirals. We implemented a pilot ED-based linkage-to-care program to address this need and evaluated the impact of the program using the HCV Care Continuum metrics. Between March 2015 and May 2016, dedicated patient care navigators identified HCV RNA-positive patients in an urban ED and offered expedited appointments with the on-site viral hepatitis clinic. Patient demographics and care continuum outcomes were abstracted from the EMR and analysed to determine significant factors influencing linkage-to-care (LTC) and treatment initiation rates. The ED linkage-to-care program achieved a 43% linkage-to-care rate (165/384), 22% treatment rate (84/384) and 16% sustained virologic response rate (63/384). Significant associations were found between linkage-to-care and increasing age (OR = 1.03), Medicare insurance (OR = 2.21) and having a primary care physician (PCP) (OR = 4.03). For patients who were linked, the odds of initiating treatment were also positively significantly associated with increasing age (OR = 1.04) and having a PCP (OR = 2.77). For patients who initiated treatment, the odds of sustained virologic response were marginally associated with having a PCP (OR = 4.92).Our ED linkage-to-care program utilized care coordination to successfully link nearly half of approached HCV RNA-positive patients to care. This design can be feasibly replicated by other EDs given limited non-clinical training required for linkage-to-care staff. Adoption of similar programs in other EDs may improve the rates of LTC and treatment initiation for previously diagnosed HCV patients.

Identifiants

pubmed: 36441638
doi: 10.1111/jvh.13774
pmc: PMC9852079
mid: NIHMS1853390
doi:

Substances chimiques

RNA 63231-63-0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

129-137

Subventions

Organisme : NIDA NIH HHS
ID : K24 DA034621
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA048063
Pays : United States

Informations de copyright

© 2022 John Wiley & Sons Ltd.

Références

Am J Emerg Med. 2002 Sep;20(5):476-80
pubmed: 12216048
Emerg Infect Dis. 2016 May;22(5):907-9
pubmed: 27089172
N Engl J Med. 1992 May 21;326(21):1399-404
pubmed: 1373867
Hepatology. 2019 Mar;69(3):1020-1031
pubmed: 30398671
PLoS One. 2018 Feb 20;13(2):e0191980
pubmed: 29462179
Ann Ig. 2007 Nov-Dec;19(6):551-7
pubmed: 18376576
Am J Manag Care. 2019 Dec 1;25(12):e379-e387
pubmed: 31860232
Scientifica (Cairo). 2012;2012:432892
pubmed: 24278694
Open Forum Infect Dis. 2016 Oct 4;3(4):ofw211
pubmed: 28066793
Clin Infect Dis. 2016 May 15;62(10):1290-1296
pubmed: 26908812
Am J Emerg Med. 2020 Jul;38(7):1396-1401
pubmed: 31836342
Hepatology. 2020 Feb;71(2):686-721
pubmed: 31816111
Clin Infect Dis. 2016 May 15;62(10):1287-1288
pubmed: 26936668
Acad Emerg Med. 2000 Sep;7(9):1036-41
pubmed: 11044001
Eur J Gastroenterol Hepatol. 2017 Jun;29(6):686-693
pubmed: 28195877
Clin Infect Dis. 2017 Jun 01;64(11):1540-1546
pubmed: 28207069
Hepatology. 2015 Mar;61(3):783-9
pubmed: 25348499
Am J Public Health. 2016 Feb;106(2):353-8
pubmed: 26562129
J Viral Hepat. 2016 Apr;23(4):274-81
pubmed: 26572798
J Viral Hepat. 2016 Jun;23(6):473-8
pubmed: 26856967
Infect Dis Clin North Am. 2017 Dec;31(4):827-838
pubmed: 29079161
JAMA. 2010 Aug 11;304(6):664-70
pubmed: 20699458
Clin Gastroenterol Hepatol. 2016 Sep;14(9):1356-60
pubmed: 27108792
Top Antivir Med. 2017 Feb/Mar;25(1):3-6
pubmed: 28402927
Am J Public Health. 2017 Jun;107(6):893-899
pubmed: 28426313
PLoS One. 2014 Jul 02;9(7):e101554
pubmed: 24988388
PLoS One. 2019 Jul 10;14(7):e0218388
pubmed: 31291275
MMWR Recomm Rep. 2020 Apr 10;69(2):1-17
pubmed: 32271723
Aliment Pharmacol Ther. 2017 Nov;46(10):992-1000
pubmed: 28949020
Open Forum Infect Dis. 2018 Jun 07;5(6):ofy076
pubmed: 29977955
CMAJ. 2001 Aug 21;165(4):415-20
pubmed: 11531049
AIDS. 2018 Nov 13;32(17):2557-2571
pubmed: 30102661
PLoS One. 2020 Sep 18;15(9):e0239393
pubmed: 32946502
Clin Infect Dis. 2016 May 1;62(9):1059-65
pubmed: 26908800

Auteurs

Zak Hyde (Z)

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Raúl Roura (R)

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Danielle Signer (D)

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Anuj Patel (A)

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Jacob Cohen (J)

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Mustapha Saheed (M)

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Sherilyn Brinkley (S)

Division Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Risha Irvin (R)

Division Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Mark S Sulkowski (MS)

Division Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

David L Thomas (DL)

Division Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Richard E Rothman (RE)

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Division Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Yu-Hsiang Hsieh (YH)

Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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