In vitro and in vivo biotransformation of glucosinolates from mashua (Tropaeolum tuberosum) by lactic acid bacteria.
Glucosinolate biotransformation
Isothiocynates
Lactic acid bacteria
Nitriles
Rats
Tropaeolum tuberosum
Journal
Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639
Informations de publication
Date de publication:
15 Mar 2023
15 Mar 2023
Historique:
received:
02
07
2022
revised:
16
09
2022
accepted:
13
10
2022
entrez:
29
11
2022
pubmed:
30
11
2022
medline:
1
12
2022
Statut:
ppublish
Résumé
Mashua (Tropaeolum tuberosum) is an Andean tuber with a high content of glucosinolates (GLSs). GLSs subjected to biotransformation by plant enzymes or enzymes of the gastrointestinal microbiota give rise to biologically active compounds, to which chemo preventive properties are attributed. In this work, the biotransformation of mashua GLSs was evaluated in vitro by six strains of lactic acid bacteria (LAB) and in vivo using rats with and without previous LAB dosing. The results showed that L. rhamnosus GG utilized the totality of glucosinalbin and glucotropaeolin, and 46.7 % of glucoaubrietin. Four GLSs derivatives were detected. The GLSs were absorbed and metabolized by the rats with low contents in feces (0.02 %) and urine (0.59 %) and were detected up to 3 h after consumption in plasma. The results showed that probiotic bacteria play an important role in transforming GLSs into beneficial compounds for the health of consumers.
Identifiants
pubmed: 36444024
pii: S0308-8146(22)02593-6
doi: 10.1016/j.foodchem.2022.134631
pii:
doi:
Substances chimiques
Glucosinolates
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
134631Informations de copyright
Copyright © 2022 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.