Validation of a risk prediction model for early chronic kidney disease in patients with type 2 diabetes: Data from the German/Austrian Diabetes Prospective Follow-up registry.


Journal

Diabetes, obesity & metabolism
ISSN: 1463-1326
Titre abrégé: Diabetes Obes Metab
Pays: England
ID NLM: 100883645

Informations de publication

Date de publication:
03 2023
Historique:
revised: 11 11 2022
received: 02 10 2022
accepted: 21 11 2022
pubmed: 30 11 2022
medline: 4 2 2023
entrez: 29 11 2022
Statut: ppublish

Résumé

To validate a recently proposed risk prediction model for chronic kidney disease (CKD) in type 2 diabetes (T2D). Subjects from the German/Austrian Diabetes Prospective Follow-up (DPV) registry with T2D, normoalbuminuria, an estimated glomerular filtration rate of 60 ml/min/1.73m Subjects (n = 10 922) had a mean age of 61 years, diabetes duration of 6 years, BMI of 31.7 kg/m The predictive model achieved moderate discrimination but good calibration in a German/Austrian T2D population, suggesting that the model may be relevant for determining CKD risk.

Identifiants

pubmed: 36444743
doi: 10.1111/dom.14925
doi:

Substances chimiques

Glycated Hemoglobin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

776-784

Informations de copyright

© 2022 John Wiley & Sons Ltd.

Références

Elshahat S, Cockwell P, Maxwell AP, Griffin M, O'Brien T, O'Neill C. The impact of chronic kidney disease on developed countries from a health economics perspective: a systematic scoping review. PLoS One. 2020;15(3):e0230512.
Hu F, Zhang T. Study on risk factors of diabetic nephropathy in obese patients with type 2 diabetes mellitus. Int J Gen Med. 2020;13:351-360.
Kainz A, Hronsky M, Stel VS, et al. Prediction of prevalence of chronic kidney disease in diabetic patients in countries of the European Union up to 2025. Nephrol Dial Transplant. 2015;30 (Suppl 4):iv113-iv118.
Giorda CB, Carna P, Salomone M, et al. Ten-year comparative analysis of incidence, prognosis, and associated factors for dialysis and renal transplantation in type 1 and type 2 diabetes versus non-diabetes. Acta Diabetol. 2018;55(7):733-740.
Deng Y, Li N, Wu Y, et al. Global, regional, and National Burden of diabetes-related chronic kidney disease from 1990 to 2019. Front Endocrinol. 2021;12:672350.
Hussain S, Chand Jamali M, Habib A, Hussain MS, Akhtar M, Najmi AK. Diabetic kidney disease: an overview of prevalence, risk factors, and biomarkers. Clin Epidemiology Glob Health. 2021;9:2-6.
Thomas MC, Brownlee M, Susztak K, et al. Diabetic kidney disease. Nat Rev Dis Primers. 2015;1:15018.
Palsson R, Patel UD. Cardiovascular complications of diabetic kidney disease. Adv Chronic Kidney Dis. 2014;21(3):273-280.
Tziomalos K, Athyros VG. Diabetic nephropathy: new risk factors and improvements in diagnosis. Rev Diabet Stud. 2015;12(1-2):110-118.
Low S, Lim SC, Zhang X, et al. Development and validation of a predictive model for chronic kidney disease progression in type 2 diabetes mellitus based on a 13-year study in Singapore. Diabetes Res Clin Pract. 2017;123:49-54.
Nelson RG, Grams ME, Ballew SH, et al. Development of risk prediction equations for incident chronic kidney disease. JAMA. 2019;322(21):2104-2114.
Afghahi H, Cederholm J, Eliasson B, et al. Risk factors for the development of albuminuria and renal impairment in type 2 diabetes-the Swedish National Diabetes Register (NDR). Nephrol Dial Transplant. 2011;26(4):1236-1243.
Basu S, Sussman JB, Berkowitz SA, Hayward RA, Yudkin JS. Development and validation of risk equations for complications of type 2 diabetes (RECODe) using individual participant data from randomised trials. Lancet Diabetes Endocrinol. 2017;5(10):788-798.
Jiang W, Wang J, Shen X, et al. Establishment and validation of a risk prediction model for early diabetic kidney disease based on a systematic review and meta-analysis of 20 cohorts. Diabetes Care. 2020;43(4):925-933.
University of Ulm. Diabetes-Patienten-Verlaufsdokumentation (DPV). https://buster.zibmt.uni-ulm.de/projekte/DPV/. Accessed May 11 2022.
Grimsmann JM, Tittel SR, Bramlage P, et al. Disease heterogeneity of adult diabetes based on routine clinical variables at diagnosis: results from the German/Austrian diabetes follow-up registry. Diabetes Obes Metab. 2022;24:2253-2262.
Bramlage P, Lanzinger S, Tittel SR, et al. Guidelines adherence in the prevention and management of chronic kidney disease in patients with diabetes mellitus on the background of recent European recommendations - a registry-based analysis. BMC Nephrol. 2021;22(1):184.
Bramlage P, Lanzinger S, Hess E, et al. Renal function deterioration in adult patients with type-2 diabetes. BMC Nephrol. 2020;21(1):312.
Inker LA, Eneanya ND, Coresh J, et al. New creatinine- and cystatin C-based equations to estimate GFR without race. N Engl J Med. 2021;385(19):1737-1749.
Moons KG, Kengne AP, Woodward M, et al. Risk prediction models: I. development, internal validation, and assessing the incremental value of a new (bio) marker. Heart. 2012;98(9):683-690.
Debray TP, Vergouwe Y, Koffijberg H, Nieboer D, Steyerberg EW, Moons KG. A new framework to enhance the interpretation of external validation studies of clinical prediction models. J Clin Epidemiol. 2015;68(3):279-289.
Alba AC, Agoritsas T, Walsh M, et al. Discrimination and calibration of clinical prediction models: Users' guides to the medical literature. JAMA. 2017;318(14):1377-1384.
Cook NR. Use and misuse of the receiver operating characteristic curve in risk prediction. Circulation. 2007;115(7):928-935.
Moons KG, Kengne AP, Grobbee DE, et al. Risk prediction models: II. External validation, model updating, and impact assessment. Heart. 2012;98(9):691-698.
Dunkler D, Gao P, Lee SF, et al. Risk prediction for early CKD in type 2 diabetes. Clin J Am Soc Nephrol. 2015;10(8):1371-1379.
Jardine MJ, Hata J, Woodward M, et al. Prediction of kidney-related outcomes in patients with type 2 diabetes. Am J Kidney Dis. 2012;60(5):770-778.
Slieker RC, van der Heijden A, Siddiqui MK, et al. Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study. BMJ. 2021;374:n2134.
Fraccaro P, van der Veer S, Brown B, et al. An external validation of models to predict the onset of chronic kidney disease using population-based electronic health records from Salford, UK. BMC Med. 2016;14:104.
Stolpe S, Kowall B, Zwanziger D, et al. External validation of six clinical models for prediction of chronic kidney disease in a German population. BMC Nephrol. 2022;23(1):272.
Lerner B, Desrochers S, Tangri N. Risk prediction models in CKD. Semin Nephrol. 2017;37(2):144-150.
Moons KG, Altman DG, Vergouwe Y, Royston P. Prognosis and prognostic research: application and impact of prognostic models in clinical practice. BMJ. 2009;338:b606.

Auteurs

Stephan Kress (S)

Medical Clinic I, Diabetes Center, Vinzentius-Hospital, Landau, Germany.

Peter Bramlage (P)

Institute for Pharmacology and Preventive Medicine, Cloppenburg, Germany.

Reinhard W Holl (RW)

Institute for Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, Germany.

Christian Dominik Möller (CD)

Bürgerhospital Frankfurt am Main, Frankfurt am Main, Germany.

Steffen Mühldorfer (S)

Gastroenterologie, Klinikum Bayreuth, Bayreuth, Germany.

Jörg Reindel (J)

Herz- und Diabeteszentrum, Klinikum Karlsburg, Karlsburg, Germany.

Jochen Seufert (J)

Division of Endocrinology and Diabetology, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Rüdiger Landgraf (R)

German Diabetes Foundation, Munich, Germany.

Ludwig Merker (L)

Diabetologie im MVZ am Park Ville d'Eu, Haan, Germany.

Sebastian M Meyhöfer (SM)

German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Institute for Endocrinology & Diabetes, University of Lübeck, Lübeck, Germany.

Thomas Danne (T)

Kinderkrankenhaus auf der Bult, Diabeteszentrum für Kinder und Jugendliche, Hannover, Germany.

Peter Fasching (P)

5th Medical Department for Endocrinology, Rheumatology and Acute Geriatrics, Clinic Ottakring, Vienna, Austria.

Peter R Mertens (PR)

Clinic of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.

Christoph Wanner (C)

Division of Nephrology, Wuerzburg University Clinic, Würzburg, Germany.

Stefanie Lanzinger (S)

Institute for Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, Germany.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH