Temporal trends in anticoagulation management for US active duty personnel with atrial fibrillation.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
29 11 2022
Historique:
entrez: 29 11 2022
pubmed: 30 11 2022
medline: 2 12 2022
Statut: epublish

Résumé

ObjectivesThis study aims to investigate US active duty (AD) military members diagnosed with atrial fibrillation (AF) and the temporal trends of systemic anticoagulation (AC). Our secondary objective is to study the AC prescriptions in AD military members diagnosed with AF and associated military dispositions and deployment rates. A retrospective investigation of Tricare pharmacy AC prescriptions within the San Antonio Military Health System from January 2004 to July 2019 for AD individuals diagnosed with AF was performed. 386 AD personnel with non-valvular AF were analysed (mean age 35.0±9.4 years; mean body mass index, 28.3±4.3 kg/m The temporal trends of systemic AC prescriptions were the primary outcome measures. The association between AC prescriptions and military dispositions and deployments were secondary outcomes of interest. The association between AC management, future deployments and military disposition was analysed using χ CHA This is the first report describing AC utilisation in US AD military members with AF. Young AD personnel with low stroke and bleeding risks do not commonly receive AC prescriptions. DOAC prescription rates are increasing and predominate over warfarin for AC indications.

Identifiants

pubmed: 36446457
pii: bmjopen-2021-049394
doi: 10.1136/bmjopen-2021-049394
pmc: PMC9710344
doi:

Substances chimiques

Warfarin 5Q7ZVV76EI
Anticoagulants 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e049394

Informations de copyright

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Andrea Nichole Keithler (AN)

Division of Cardiology, Brooke Army Medical Center, Fort Sam Houston, Texas, USA.

Andrew S Wilson (AS)

Division of Cardiology, Brooke Army Medical Center, Fort Sam Houston, Texas, USA.

Alexander Yuan (A)

Division of Cardiology, Brooke Army Medical Center, Fort Sam Houston, Texas, USA.

Jose M Sosa (JM)

Division of Cardiology, Brooke Army Medical Center, Fort Sam Houston, Texas, USA.

Kelvin N V Bush (KNV)

Division of Cardiology, Brooke Army Medical Center, Fort Sam Houston, Texas, USA kelvin.n.bush.mil@health.mil.

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Classifications MeSH