Ultrafast laser surgery probe for sub-surface ablation to enable biomaterial injection in vocal folds.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
29 11 2022
29 11 2022
Historique:
received:
09
09
2022
accepted:
15
11
2022
entrez:
29
11
2022
pubmed:
30
11
2022
medline:
2
12
2022
Statut:
epublish
Résumé
Creation of sub-epithelial voids within scarred vocal folds via ultrafast laser ablation may help in localization of injectable therapeutic biomaterials towards an improved treatment for vocal fold scarring. Several ultrafast laser surgery probes have been developed for precise ablation of surface tissues; however, these probes lack the tight beam focusing required for sub-surface ablation in highly scattering tissues such as vocal folds. Here, we present a miniaturized ultrafast laser surgery probe designed to perform sub-epithelial ablation in vocal folds. The requirement of high numerical aperture for sub-surface ablation, in addition to the small form factor and side-firing architecture required for clinical use, made for a challenging optical design. An Inhibited Coupling guiding Kagome hollow core photonic crystal fiber delivered micro-Joule level ultrashort pulses from a high repetition rate fiber laser towards a custom-built miniaturized objective, producing a 1/e
Identifiants
pubmed: 36446830
doi: 10.1038/s41598-022-24446-5
pii: 10.1038/s41598-022-24446-5
pmc: PMC9708667
doi:
Substances chimiques
Biocompatible Materials
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
20554Subventions
Organisme : NIDCD NIH HHS
ID : R01 DC014783
Pays : United States
Informations de copyright
© 2022. The Author(s).
Références
Laryngoscope. 2009 Nov;119(11):2182-6
pubmed: 19676103
Biomaterials. 2006 Mar;27(7):1104-9
pubmed: 16154633
Opt Express. 2008 Jun 23;16(13):9996-10005
pubmed: 18575570
Acta Otolaryngol. 2006 Jul;126(7):758-63
pubmed: 16803717
Biomed Opt Express. 2016 Oct 19;7(11):4639-4653
pubmed: 27896003
Appl Opt. 2020 Oct 1;59(28):8806-8813
pubmed: 33104564
J Speech Lang Hear Res. 1998 Feb;41(1):S101-16
pubmed: 9493749
J Biomed Opt. 2012 Mar;17(3):038002
pubmed: 22502583
Biomed Opt Express. 2021 Jul 12;12(8):4779-4794
pubmed: 34513224
Sci Rep. 2016 Feb 11;6:20950
pubmed: 26864679
Laryngoscope. 2014 Mar;124(3):E64-72
pubmed: 24115025
Sci Rep. 2020 Nov 20;10(1):20261
pubmed: 33219260
Laryngoscope. 2012 Feb;122(2):343-8
pubmed: 22271658
J Biomed Opt. 2006 Jul-Aug;11(4):041117
pubmed: 16965145
Biomed Opt Express. 2018 Apr 23;9(5):2304-2311
pubmed: 29760989
Ann Otol Rhinol Laryngol. 2005 Sep;114(9):662-70
pubmed: 16240927
J Neurosci Methods. 2006 Sep 30;156(1-2):351-9
pubmed: 16621010
J Biomed Opt. 2022 Aug;27(8):
pubmed: 36008882
Phys Rev Lett. 2008 Jan 25;100(3):038102
pubmed: 18233040
Opt Express. 2011 May 23;19(11):10536-52
pubmed: 21643308
Laryngoscope. 1998 Mar;108(3):393-7
pubmed: 9504613
Clin Otolaryngol. 2009 Oct;34(5):460-6
pubmed: 19793279
Acta Biomater. 2019 Mar 15;87:97-107
pubmed: 30708064
Ann Otol Rhinol Laryngol. 2011 Mar;120(3):175-84
pubmed: 21510143
J Biomed Opt. 2019 Aug;24(8):1-7
pubmed: 31468749
Otolaryngol Head Neck Surg. 1996 Nov;115(5):474-82
pubmed: 8903451
J Biophotonics. 2016 Jan;9(1-2):171-80
pubmed: 26260774
Eur Arch Otorhinolaryngol. 2013 Sep;270(9):2491-507
pubmed: 23605306
Chem Rev. 2003 Feb;103(2):577-644
pubmed: 12580643
Biomed Opt Express. 2014 Jun 02;5(7):2023-36
pubmed: 25071946
J Voice. 2009 Jul;23(4):399-407
pubmed: 18395421
J Biomed Opt. 2016 Nov 1;21(11):115004
pubmed: 27901549
Biomacromolecules. 2006 Dec;7(12):3336-44
pubmed: 17154461