Drug-Coated Balloon for the Treatment of Small Vessel Coronary Artery Disease - A Randomized Non-Inferiority Trial.


Journal

Circulation journal : official journal of the Japanese Circulation Society
ISSN: 1347-4820
Titre abrégé: Circ J
Pays: Japan
ID NLM: 101137683

Informations de publication

Date de publication:
25 01 2023
Historique:
pubmed: 1 12 2022
medline: 28 1 2023
entrez: 30 11 2022
Statut: ppublish

Résumé

Drug-coated balloons (DCB) have shown promising results for the treatment of in-stent restenosis (ISR) and small vessel disease (SVD). However, data comparing the treatment efficacy of different DCBs are limited.Methods and Results: AGENT Japan is a prospective randomized controlled trial that compares the Agent balloon coated with a low-dose formulation of paclitaxel (2 μg/mm Data from this study demonstrate good clinical outcomes with the Agent DCB when used to treat patients with SVD or ISR.

Sections du résumé

BACKGROUND
Drug-coated balloons (DCB) have shown promising results for the treatment of in-stent restenosis (ISR) and small vessel disease (SVD). However, data comparing the treatment efficacy of different DCBs are limited.Methods and Results: AGENT Japan is a prospective randomized controlled trial that compares the Agent balloon coated with a low-dose formulation of paclitaxel (2 μg/mm
CONCLUSIONS
Data from this study demonstrate good clinical outcomes with the Agent DCB when used to treat patients with SVD or ISR.

Identifiants

pubmed: 36450540
doi: 10.1253/circj.CJ-22-0584
doi:

Substances chimiques

Paclitaxel P88XT4IS4D

Types de publication

Randomized Controlled Trial Equivalence Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

287-295

Auteurs

Masato Nakamura (M)

Toho University Ohashi Medical Center.

Tsuyoshi Isawa (T)

Sendai Kousei Hospital.

Shigeru Nakamura (S)

Kyoto-Katsura Hospital.

Kenji Ando (K)

Kokura Memorial Hospital.

Atsuo Namiki (A)

Kanto Rosai Hospital.

Yoshisato Shibata (Y)

Miyazaki Medical Association Hospital.

Toshiro Shinke (T)

Showa University Hospital.

Yoshiaki Ito (Y)

Saiseikai Yokohama-City Eastern Hospital.

Kenshi Fujii (K)

Sakurabashi Watanabe Hospital.

Junya Shite (J)

Osaka Saiseikai Nakatsu Hospital.

Ken Kozuma (K)

Teikyo University Hospital.

Shigeru Saito (S)

Shonan Kamakura General Hospital.

Junichi Yamaguchi (J)

Tokyo Women's Medical University Hospital.

Seiji Yamazaki (S)

Sapporo Higashi Tokushukai Hospital.

Paul Underwood (P)

Boston Scientific Corporation.

Dominic J Allocco (DJ)

Boston Scientific Corporation.

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Classifications MeSH