Head and neck small-cell carcinoma: A multicenter study of 39 cases from 10 institutions.
concurrent chemoradiotherapy
diagnostic and therapeutic algorithms
head and neck carcinoma
neuroendocrine carcinoma
small-cell carcinoma
Journal
Frontiers in surgery
ISSN: 2296-875X
Titre abrégé: Front Surg
Pays: Switzerland
ID NLM: 101645127
Informations de publication
Date de publication:
2022
2022
Historique:
received:
20
09
2022
accepted:
05
10
2022
entrez:
1
12
2022
pubmed:
2
12
2022
medline:
2
12
2022
Statut:
epublish
Résumé
Basal information of head and neck small-cell carcinoma (HNSmCC) including epidemiology, primary site, treatment, and prognosis remains sparse due to its rarity. We report here a multicenter retrospective study on the diagnosis, treatment, and outcomes of patients with HNSmCC. This study involved 47 patients with HNSmCC from 10 participating institutions. Eight patients were excluded for whom no pathological specimens were available ( As pretreatment examinations, computed tomography (CT) was performed for the brain ( Neck and chest CT, neck MRI, and PET-CT would be necessary and sufficient examinations in the diagnostic set up for HNSmCC. CCRT may be recommended as the first-line treatment. The 1-year/2-year OS was 65.3%/53.3%. This study would provide basal data for a proposing the diagnostic and treatment algorithms for HNSmCC.
Identifiants
pubmed: 36451679
doi: 10.3389/fsurg.2022.1049116
pmc: PMC9701733
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1049116Informations de copyright
© 2022 Matsuyama, Ueki, Okamoto, Nagao, Honda, Yamazaki, Okabe, Togashi, Shodo, Ota, Takahashi, Omata, Yokoyama, Saijo, Tanaka, Tsukahara, Kitahara, Uemura, Yoshimoto, Matsumoto, Okami, Sakai, Takano, Kondo, Inohara, Eguchi, Oridate, Tanabe, Nakamizo, Yokoshima, Miura, Kitani and Horii.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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