Use of Dual-Energy X-ray Absorptiometry in Children with Inflammatory Bowel Disease: A Large Single Centre Study.
Absorptiometry, photon
Child
Inflammatory bowel disease
Journal
Pediatric gastroenterology, hepatology & nutrition
ISSN: 2234-8646
Titre abrégé: Pediatr Gastroenterol Hepatol Nutr
Pays: Korea (South)
ID NLM: 101590471
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
received:
10
02
2022
revised:
28
05
2022
revised:
08
08
2022
accepted:
23
08
2022
entrez:
1
12
2022
pubmed:
2
12
2022
medline:
2
12
2022
Statut:
ppublish
Résumé
Low bone mineral density (BMD) is a complication in children with inflammatory bowel disease (IBD). There are limited data evaluating dual-energy x-ray absorptiometry (DXA) as a screening tool for low BMD in children with IBD. We performed a single site retrospective analysis of DXA use. Children aged 5-18 years with IBD diagnosed between 2013 to 2017 at the Royal Children's Hospital, Australia, were included. Patient demographics, measures of disease activity, DXA scores, and factors related to BMD were collected. Over a median follow up of 5.1 (4-6.4) years, 72/239 (30.1%) children underwent DXA, and 28/239 (11.7%) children had a second DXA. Our DXA practice differed to consensus guidelines regarding initial screening based on height and/or body mass index (BMI) z-score (8/17 [47.1%]), and repeat surveillance (13/42 [31.0%]). Children had a median lumbar spine (LS) z-score -0.80 (-1.65-0.075). Children with LS z-score≤-2.0 (n=14) had lower weight (6.57 [1.78-23.7] vs. 51.1 [26.5-68.7], Children with IBD had low BMD. In addition to height centile and weight centile, FCP was associated with lower BMD, and should be considered in DXA screening guidelines. Greater clinician awareness of DXA consensus guidelines is required. Future prospective studies are required.
Identifiants
pubmed: 36451689
doi: 10.5223/pghn.2022.25.6.473
pmc: PMC9679306
doi:
Types de publication
Journal Article
Langues
eng
Pagination
473-480Informations de copyright
Copyright © 2022 by The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition.
Déclaration de conflit d'intérêts
Conflict of Interest: The authors have no financial conflicts of interest.
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