Resistance Mechanism and Physiological Effects of Microcin Y in Salmonella enterica subsp.

Anti-Bacterial Agents / pharmacology Salmonella enterica / drug effects Salmonella typhimurium / drug effects Serogroup Bacteriocins / pharmacology
MccY Salmonella Salmonella Typhimurium Ton system drug resistance mechanisms lasso peptide resistance virulence virulence factors

Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
21 12 2022
Historique:
pubmed: 2 12 2022
medline: 28 12 2022
entrez: 1 12 2022
Statut: ppublish

Résumé

Salmonella bacteria pose a significant threat to animal husbandry and human health due to their virulence and multidrug resistance. The lasso peptide MccY is a recently discovered antimicrobial peptide that acts against various serotypes of Salmonella. In this study, we further explore the resistance mechanism and activity of MccY. Mutants of Ton system genes, including

Identifiants

DOI: 10.1128/spectrum.01859-22 PMID: 36453909 PMC: PMC9769762
pubmed: 36453909
doi: 10.1128/spectrum.01859-22
pmc: PMC9769762
doi:

Substances chimiques

Anti-Bacterial Agents 0
microcin 1403-96-9
Bacteriocins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0185922

Auteurs

Yu Han (Y)

College of Veterinary Medicine, South China Agricultural Universitygrid.20561.30, Guangzhou, China.

Yu Li (Y)

College of Veterinary Medicine, South China Agricultural Universitygrid.20561.30, Guangzhou, China.

Zhiwei Zeng (Z)

College of Veterinary Medicine, South China Agricultural Universitygrid.20561.30, Guangzhou, China.

Wenjing Li (W)

College of Veterinary Medicine, South China Agricultural Universitygrid.20561.30, Guangzhou, China.

Saixiang Feng (S)

College of Veterinary Medicine, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, Guangzhou, China.
Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs, Guangzhou, China.
Key Laboratory of Veterinary Vaccine Innovation of the Ministry of Agriculture and Rural Affairs, Guangzhou, China.
National and Regional Joint Engineering Laboratory for Medicament of Zoonosis Prevention and Control, Guangzhou, China.
ORCID: 0000-0002-7239-3531

Weisheng Cao (W)

College of Veterinary Medicine, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, Guangzhou, China.
Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs, Guangzhou, China.
Key Laboratory of Veterinary Vaccine Innovation of the Ministry of Agriculture and Rural Affairs, Guangzhou, China.
National and Regional Joint Engineering Laboratory for Medicament of Zoonosis Prevention and Control, Guangzhou, China.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Resistance Mechanism and Physiological Effects...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Salmonella › Salmonella enterica › Resistance Mechanism and Physiological Effects...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Salmonella › Salmonella enterica › Salmonella typhimurium › Resistance Mechanism and Physiological Effects...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Sérogroupe › Resistance Mechanism and Physiological Effects...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Perforines › Bactériocines › Resistance Mechanism and Physiological Effects...