Prognostic value of a comprehensive geriatric assessment for predicting one-year mortality in presumably frail patients with symptomatic aortic stenosis.

aortic stenosis comprehensive geriatric assessment frailty transcatheter aortic valve implantation

Journal

Archives of medical science : AMS
ISSN: 1734-1922
Titre abrégé: Arch Med Sci
Pays: Poland
ID NLM: 101258257

Informations de publication

Date de publication:
2022
Historique:
received: 03 12 2018
accepted: 16 05 2019
entrez: 2 12 2022
pubmed: 24 3 2021
medline: 24 3 2021
Statut: epublish

Résumé

Despite suffering a severe aortic stenosis, some patients are denied either surgical or transcatheter aortic valve implantation (TAVI) therapy because of a frail condition. We aimed to identify whether a comprehensive geriatric assessment (CGA) might be useful to predict the prognosis of presumably frail patients with severe aortic stenosis. Between March 2011 and July 2016, 818 patients were consecutively and prospectively enrolled. 161 had a CGA and were considered for analysis. Considering combined CGA and heart team recommendations, 102 TAVI procedures were performed (TAVI group) and 59 patients constituted the no-TAVI group. The primary endpoint was all-cause mortality at 1 year. There was no difference between the TAVI and the no-TAVI groups considering morphometric data, cardiovascular risk factors or symptoms. The no-TAVI group had higher surgical risk (logistic EuroSCORE1 33.4 ±17.8 vs. 22.7 ±14.9; One-year mortality was higher in geriatric-assessed frail patients who did not undergo TAVI. FTSST, which assesses patients' mobility, was the only prognostic marker for 1-year mortality, on top of the usual medical parameters.

Identifiants

pubmed: 36457965
doi: 10.5114/aoms/109391
pii: 109391
pmc: PMC9710260
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1446-1452

Informations de copyright

Copyright: © 2021 Termedia & Banach.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

J Am Coll Cardiol. 1995 Nov 15;26(6):1522-8
pubmed: 7594080
Eur Heart J. 2005 Dec;26(24):2714-20
pubmed: 16141261
Pain. 2005 Oct;117(3):412-420
pubmed: 16153776
Eur J Neurol. 2013 Mar;20(3):588-590
pubmed: 22913655
Heart. 2017 Dec;103(24):1970-1976
pubmed: 28684438
J Gerontol A Biol Sci Med Sci. 2007 Jul;62(7):731-7
pubmed: 17634320
J Am Geriatr Soc. 1992 Nov;40(11):1129-34
pubmed: 1401698
Soins Gerontol. 1998 Jun;(13):23-7
pubmed: 9735854
J Am Coll Cardiol. 2011 Nov 8;58(20):2130-8
pubmed: 22019110
J Am Geriatr Soc. 2008 Aug;56(8):1575-7
pubmed: 18808608
Am Heart J. 1980 Apr;99(4):419-24
pubmed: 7189084
Eur Heart J. 2017 Sep 21;38(36):2739-2791
pubmed: 28886619
Mayo Clin Proc. 1987 Nov;62(11):986-91
pubmed: 3312856
Eur Heart J. 2003 Jul;24(13):1231-43
pubmed: 12831818
N Engl J Med. 2012 May 3;366(18):1705-15
pubmed: 22551129
Neurology. 2014 Sep 2;83(10):920-8
pubmed: 25098535
J Nutr Health Aging. 2009 Apr;13(4):390-4
pubmed: 19300888
J Am Coll Cardiol. 2010 Nov 9;56(20):1668-76
pubmed: 21050978
J Gerontol A Biol Sci Med Sci. 2005 Oct;60(10):1304-9
pubmed: 16282564
Circulation. 1982 Nov;66(5):1105-10
pubmed: 7127696
Curr Cardiol Rep. 2011 Jun;13(3):173-4
pubmed: 21336623
Int J Cardiol. 2015 Mar 15;183:98-104
pubmed: 25662059
J Physiother. 2016 Jul;62(3):171
pubmed: 27298055
Circ Cardiovasc Interv. 2017 Sep;10(9):
pubmed: 28916601
Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2794-802
pubmed: 22936341
J Nutr Health Aging. 2009 Nov;13(9):782-8
pubmed: 19812868
EuroIntervention. 2015 Jan;10(9):e1-9
pubmed: 25599700
Eur Heart J Qual Care Clin Outcomes. 2017 Apr 1;3(2):123-132
pubmed: 28927173
Autoimmun Rev. 2013 Aug;12(10):976-89
pubmed: 23542507
Prog Cardiovasc Dis. 2014 May-Jun;56(6):572-82
pubmed: 24838133
J Am Coll Cardiol. 2015 Apr 14;65(14):1472-80
pubmed: 25857913
Circ Res. 2013 Jul 5;113(2):223-37
pubmed: 23833296
Cancer Control. 2003 Nov-Dec;10(6):454-62
pubmed: 14652521

Auteurs

Audrey Camarzana (A)

Institut Mitovasc, University of Angers, Angers, France.

Cédric Annweiler (C)

Department of Geriatric Medicine, University Memory Center, Research Center on Autonomy and Longevity, University Hospital, Angers, France; UPRES EA 4638, University of Angers, Angers, France.

Frédéric Pinaud (F)

Department of Cardiac Surgery, University Hospital of Angers, Angers, France.

Wissam Abi-Khalil (W)

Institut Mitovasc, University of Angers, UMR CNRS 6015-INSERMU1083, Angers, France.

Frédéric Rouleau (F)

Institut Mitovasc, University of Angers, UMR CNRS 6015-INSERMU1083, Angers, France.

Guillaume Duval (G)

Department of Geriatric Medicine, University Memory Center, Research Center on Autonomy and Longevity, University Hospital, Angers, France; UPRES EA 4638, University of Angers, Angers, France.

Fabrice Prunier (F)

Institut Mitovasc, University of Angers, UMR CNRS 6015-INSERMU1083, Angers, France.

Alain Furber (A)

Institut Mitovasc, University of Angers, UMR CNRS 6015-INSERMU1083, Angers, France.

Loïc Biere (L)

Institut Mitovasc, University of Angers, UMR CNRS 6015-INSERMU1083, Angers, France.

Classifications MeSH