Efficacy of Two-phase Treatment Regimen for Rhino-facial Entomophthoromycosis: Our Experience and Review of Literature.
Azoles
Basidiobolomycosis
Entomophthoromycosis
India
Potassium Iodide
Skin
Zygomycosis
Journal
Oman medical journal
ISSN: 1999-768X
Titre abrégé: Oman Med J
Pays: Oman
ID NLM: 101526350
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
received:
19
11
2020
accepted:
19
05
2021
entrez:
2
12
2022
pubmed:
3
12
2022
medline:
3
12
2022
Statut:
epublish
Résumé
This paper reviews our institutional experience in the management of rhino-facial entomophthoromycosis, a rare subcutaneous fungal infection. We adopt a fixed two-phase protocol comprising an initial 'intensive phase' (two-drug regimen) followed by an 'eradication phase' (monotherapy). We present five patients treated between May 2013 and May 2020 in our institution who were subjected to the mentioned protocol. All five patients received six months of supersaturated potassium iodide solution and itraconazole, followed by four months of monotherapy with only supersaturated potassium iodide solution. All patients responded well to the treatment and were disease-free on follow-up of a minimum two years post-treatment. We recommend this procedure for all typical cases of entomophthoromycosis and suggest avoiding surgical intervention which may disseminate the fungus and delay response to treatment.
Identifiants
pubmed: 36458237
doi: 10.5001/omj.2022.29
pii: OMJ-37-06-2000230
pmc: PMC9664314
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e448Informations de copyright
The OMJ is Published Bimonthly and Copyrighted 2022 by the OMSB.
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