Genome-wide association study analysis to resolve the key regulatory mechanism of biomineralization in Pinctada fucata martensii.
Pinctada fucata martensii
SNP
biomineralization-controlled trait
genome
genome-wide association study
growth
selective sweep
Journal
Molecular ecology resources
ISSN: 1755-0998
Titre abrégé: Mol Ecol Resour
Pays: England
ID NLM: 101465604
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
revised:
17
11
2022
received:
22
10
2021
accepted:
30
11
2022
pubmed:
3
12
2022
medline:
8
3
2023
entrez:
2
12
2022
Statut:
ppublish
Résumé
Biomineralization-controlled exo-/endoskeleton growth contributes to body growth and body size diversity. Molluscan shells undergo ectopic biomineralization to form the exoskeleton and biocalcified "pearl" involved in invading defence. Notably, exo-/endoskeletons have a common ancestral origin, but their regulation and body growth are largely unknown. This study employed the pearl oyster, Pinctada fucata marntensii, a widely used experimental model for biomineralization in invertebrates, to perform whole-genome resequencing of 878 individuals from wild and breeding populations. This study characterized the genetic architecture of biomineralization-controlled growth and ectopic biomineralization. The insulin-like growth factor (IGF) endocrine signal interacted with ancient single-copy transcription factors to form the regulatory network. Moreover, the "cross-phylum" regulation of key long noncoding RNA (lncRNA) in bivalves and mammals indicated the conserved genetic and epigenetic regulation in exo-/endoskeleton growth. Thyroid hormone signal and apoptosis regulation in pearl oysters affected ectopic biomineralization in pearl oyster. These findings provide insights into the mechanism underlying the evolution and regulation of biomineralization in exo-/endoskeleton animals and ectopic biomineralization.
Identifiants
pubmed: 36458936
doi: 10.1111/1755-0998.13743
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
680-693Subventions
Organisme : China Agriculture Research System of MOF and MARA
Organisme : Department of Science and Technology of Guangdong Province
ID : 2021B0202020003
Organisme : Guangdong Basic and Applied Basic Research Foundation
ID : 2019A1515011096
Organisme : Guangdong Basic and Applied Basic Research Foundation
ID : 2019A1515111026
Organisme : Guangdong Basic and Applied Basic Research Foundation
ID : 2020A1515010691
Organisme : Guangdong Basic and Applied Basic Research Foundation
ID : 2021A1515011199
Organisme : Guangdong Provincial Special Fund For Modern Agriculture Industry Technology Innovation Teams, Department of Agriculture and Rurual Affairs of Guangdong Province
ID : 2020KJ146
Organisme : Innovation Team Project from the Department of Education of Guangdong Province
ID : 2021KCXTD026
Organisme : National Natural Science Foundation of China
ID : 32002369
Organisme : National Natural Science Foundation of China
ID : 32102817
Informations de copyright
© 2022 John Wiley & Sons Ltd.
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