Computed tomographic airway morphology after targeted lung denervation treatment in COPD.
Journal
Respiratory medicine
ISSN: 1532-3064
Titre abrégé: Respir Med
Pays: England
ID NLM: 8908438
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
received:
16
08
2022
revised:
11
11
2022
accepted:
22
11
2022
pubmed:
3
12
2022
medline:
4
1
2023
entrez:
2
12
2022
Statut:
ppublish
Résumé
This post-hoc analysis of the AIRFLOW-2 trial investigated the changes in airway CT-parameters after targeted lung denervation (TLD) and whether these changes are associated with treatment response. In the treatment group (n = 32), an improvement in air trapping was significantly associated with an improvement in residual volume (RV). Furthermore, improvements in Pi10 and airway lumen were significantly associated with an improvement in both RV and FEV
Identifiants
pubmed: 36459953
pii: S0954-6111(22)00324-9
doi: 10.1016/j.rmed.2022.107059
pii:
doi:
Types de publication
Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
107059Investigateurs
Arschang Valipour
(A)
Christine Abele
(C)
Irene Firlinger
(I)
Kiran Kothakuzhakal
(K)
Marina Duller
(M)
Bernd Lamprecht
(B)
Roland Kropfmueller
(R)
Kornelia Holzmann
(K)
Sandra Rathmeier
(S)
Ralf Hubner
(R)
Leonore Erdmann
(L)
Bettina Temmesfeld-Wollbrück
(B)
Christoph Ruwwe Glösenkamp
(C)
Wolfgang Gesierich
(W)
Frank Reichenberger
(F)
Christa Niehaus
(C)
Felix Herth
(F)
Ralf Eberhardt
(R)
Daniela Gompelmann
(D)
Brigitte Rump
(B)
Kaid Darwiche
(K)
Stephan Eisenmann
(S)
Ulrike Kaiser
(U)
Birte Schwarz
(B)
Ulrike Sampel
(U)
Christian Schumann
(C)
Robert Kaiser
(R)
Kathryn Schumann-Stoiber
(K)
Dirk Skowasch
(D)
Sabine Ring
(S)
Christophe Pison
(C)
Amandine Briault
(A)
Francois Arbib
(F)
Marie Jondot
(M)
Thierry Perez
(T)
Clement Fournier
(C)
Regis Matran
(R)
Michele Catto
(M)
Nathalie Bautin
(N)
Virginie De Broucker
(V)
Marie Willemin
(M)
Anne Prevotat
(A)
Ludivine Wemeau
(L)
Alice Gicquello
(A)
Morgane Foulon
(M)
Hasna Camara
(H)
Gaetan Deslee
(G)
Herve Vallerand
(H)
Sandra Dury
(S)
Delphine Gras
(D)
Margaux Bonnaire-Verdier
(M)
Romain Kessler
(R)
Sandrine Hirschi
(S)
Michele Porzio
(M)
Tristan Degot
(T)
Mathieu Canuet
(M)
Armelle Schuller
(A)
Julien Stauder
(J)
Sahra Ali Azouaou
(SA)
Armelle Marceau
(A)
Hervé Mal
(H)
Yolande Costa
(Y)
Pallav L Shah
(PL)
Justin Garner
(J)
Karthi Srikanthan
(K)
Cielito Caneja
(C)
John Thornton
(J)
Dirk-Jan Slebos
(DJ)
Nick Ten Hacken
(NT)
Jorine Hartman
(J)
Karin Klooster
(K)
Sonja Augustijn
(S)
Peter Bonta
(P)
Jouke Annema
(J)
Marianne van de Pol
(M)
Annika Goorsenberg
(A)
Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest DJS is a PI for Nuvaira, USA and reports consultancy fees from Nuvaira paid to the institution. AV reports speaker fees from Nuvaira in the past. PS reports clinical trial expenses reimbursed to the host institutions in the past 36 months. CP reports payments for lectures and to CHUGA to conduct phase 3 trials from Nuvaira (AIRFLOW 2 and 3 trials), GSK, AZ, Boehringer Ingelheim, Novartis and Chiesi. JH and FH have nothing to disclose.