Ultrafast light-induced dynamics in the microsolvated biomolecular indole chromophore with water.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
03 12 2022
03 12 2022
Historique:
received:
10
03
2021
accepted:
04
10
2022
pubmed:
3
12
2022
medline:
7
12
2022
entrez:
2
12
2022
Statut:
epublish
Résumé
Interactions between proteins and their solvent environment can be studied in a bottom-up approach using hydrogen-bonded chromophore-solvent clusters. The ultrafast dynamics following UV-light-induced electronic excitation of the chromophores, potential radiation damage, and their dependence on solvation are important open questions. The microsolvation effect is challenging to study due to the inherent mix of the produced gas-phase aggregates. We use the electrostatic deflector to spatially separate different molecular species in combination with pump-probe velocity-map-imaging experiments. We demonstrate that this powerful experimental approach reveals intimate details of the UV-induced dynamics in the near-UV-absorbing prototypical biomolecular indole-water system. We determine the time-dependent appearance of the different reaction products and disentangle the occurring ultrafast processes. This approach ensures that the reactants are well-known and that detailed characteristics of the specific reaction products are accessible - paving the way for the complete chemical-reactivity experiment.
Identifiants
pubmed: 36460654
doi: 10.1038/s41467-022-33901-w
pii: 10.1038/s41467-022-33901-w
pmc: PMC9718776
doi:
Substances chimiques
Water
059QF0KO0R
Indoles
0
Solvents
0
Hydrogen
7YNJ3PO35Z
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
7462Informations de copyright
© 2022. The Author(s).
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