Trace determination of prohibited acrylamide in cosmetic products by vortex-assisted reversed-phase dispersive liquid-liquid microextraction and liquid chromatography-tandem mass spectrometry.
Acrylamide
Cosmetic products
Liquid chromatography-mass spectrometry
Reversed-phase dispersive liquid-liquid microextraction
Journal
Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488
Informations de publication
Date de publication:
04 Jan 2023
04 Jan 2023
Historique:
received:
20
09
2022
revised:
10
11
2022
accepted:
13
11
2022
pubmed:
4
12
2022
medline:
28
12
2022
entrez:
3
12
2022
Statut:
ppublish
Résumé
An analytical method for the determination of residual acrylamide in cosmetic products containing potential acrylamide-releasing ingredients is presented. The method is based on vortex-assisted reversed-phase dispersive liquid-liquid microextraction (VA-RP-DLLME) to extract and preconcentrate acrylamide by using water as extraction solvent taking advantage the highly polar behavior of this analyte, followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) for its determination. Under optimized conditions (5 mL toluene as supporting solvent, 50 µL of water as extraction solvent, 1 min for vortex extraction time) the method was properly validated obtaining good analytical features (linearity up to 20 ng mL
Identifiants
pubmed: 36462477
pii: S0021-9673(22)00842-1
doi: 10.1016/j.chroma.2022.463651
pii:
doi:
Substances chimiques
Acrylamide
20R035KLCI
Solvents
0
Water
059QF0KO0R
Cosmetics
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
463651Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.