FLASHlab@PITZ: New R&D platform with unique capabilities for electron FLASH and VHEE radiation therapy and radiation biology under preparation at PITZ.

FLASH and VHEE radiation therapy Flexible electron accelerator Online image guiding Ultra-high dose rate Uniquely wide parameter range

Journal

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
ISSN: 1724-191X
Titre abrégé: Phys Med
Pays: Italy
ID NLM: 9302888

Informations de publication

Date de publication:
Dec 2022
Historique:
received: 27 04 2022
revised: 19 09 2022
accepted: 31 10 2022
pubmed: 5 12 2022
medline: 15 12 2022
entrez: 4 12 2022
Statut: ppublish

Résumé

At the Photo Injector Test facility at DESY in Zeuthen (PITZ), an R&D platform for electron FLASH and very high energy electron radiation therapy and radiation biology is being prepared (FLASHlab@PITZ). The beam parameters available at PITZ are worldwide unique. They are based on experiences from 20 + years of developing high brightness beam sources and an ultra-intensive THz light source demonstrator for ps scale electron bunches with up to 5 nC bunch charge at MHz repetition rate in bunch trains of up to 1 ms length, currently 22 MeV (upgrade to 250 MeV planned). Individual bunches can provide peak dose rates up to 10

Identifiants

pubmed: 36463582
pii: S1120-1797(22)02087-7
doi: 10.1016/j.ejmp.2022.10.026
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

174-187

Informations de copyright

Copyright © 2022 Associazione Italiana di Fisica Medica e Sanitaria. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Frank Stephan (F)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany. Electronic address: frank.stephan@desy.de.

Matthias Gross (M)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Anna Grebinyk (A)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Zakaria Aboulbanine (Z)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany; On Leave from University Mohammed V, Rabat, Morocco.

Zohrab Amirkhanyan (Z)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany; On Leave from CANDLE Synchrotron Research Institute, Yerevan, Armenia.

Volker Budach (V)

Department of Radiotherapy, Charité Berlin, CCM/CVK, 13353 Berlin, Germany.

Vincent Henrique Ehrhardt (VH)

University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20251 Hamburg, Germany.

Angeles Faus-Golfe (A)

Laboratoire de Physique des 2 Infinies, Irene Joliot-Curie Laboratory IJCLab, CNRS/IN2P3, Universit́e Paris-Saclay, Orsay 91898, France.

Marcus Frohme (M)

Technical University of Applied Sciences Wildau, Hochschulring 1, 15745 Wildau, Germany.

Jean-Francois Germond (JF)

CHUV, Institut de Radiophysique, Rue du Grand-Pré 1, CH-1007 Lausanne, Switzerland.

James David Good (JD)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Florian Grüner (F)

Universität Hamburg and Center for Free-Electron Laser Science, Luruper Chaussee 149, 22761 Hamburg, Germany.

David Kaul (D)

Department of Radiotherapy, Charité Berlin, CCM/CVK, 13353 Berlin, Germany.

Mikhail Krasilnikov (M)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Ron Leavitt (R)

CHUV, Service de Radio-Oncologie, Rue du Bugnon 46, CH-1011 Lausanne, Switzerland.

Wim Leemans (W)

Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22603 Hamburg, Germany.

Xiangkun Li (X)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Gregor Loisch (G)

Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22603 Hamburg, Germany.

Frieder Müller (F)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Georg Müller (G)

Karlsruhe Institute of Technology (KIT), Institute for Pulsed Power and Microwave Technology (IHM), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.

Frank Obier (F)

Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22603 Hamburg, Germany.

Anne Oppelt (A)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Sebastian Philipp (S)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Houjun Qian (H)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Judith Reindl (J)

Universität der Bundeswehr München, Werner-Heisenberg-Weg 39, 85577 Neubiberg, Germany.

Felix Riemer (F)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Martin Sack (M)

Karlsruhe Institute of Technology (KIT), Institute for Pulsed Power and Microwave Technology (IHM), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.

Michael Schmitz (M)

Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22603 Hamburg, Germany.

Tobias Schnautz (T)

Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22603 Hamburg, Germany.

Andreas Schüller (A)

Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, Braunschweig 38116, Germany.

Theresa Staufer (T)

Universität Hamburg and Center for Free-Electron Laser Science, Luruper Chaussee 149, 22761 Hamburg, Germany.

Christian Stegmann (C)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Gohar Tsakanova (G)

Institute of Molecular Biology NAS RA, Yerevan, Armenia; CANDLE Synchrotron Research Institute, Yerevan, Armenia.

Marie-Catherine Vozenin (MC)

CHUV, Service de Radio-Oncologie, Rue du Bugnon 46, CH-1011 Lausanne, Switzerland.

Hans Weise (H)

Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22603 Hamburg, Germany.

Steven Worm (S)

Deutsches Elektronen-Synchrotron DESY, Platanenallee 6, 15738 Zeuthen, Germany.

Daniel Zips (D)

Department of Radiotherapy, Charité Berlin, CCM/CVK, 13353 Berlin, Germany.

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