Microbiota Dysbiosis a Cause of Colorectal Cancer or Not? A Systematic Review.
colerectal carcinogenesis
microbes and colorectal cancer
microbes associated with crc
microbes or ("microbiota" [all fields] or "microbiome" [all fields]) and ("colorectal cancer" [all fields] or "colorectal carcinogenesis" [all fields] or "colon cancer" [all fields] or "rectal cancer" [all fields])
microbial dysbiosis
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
received:
26
07
2022
accepted:
30
10
2022
entrez:
5
12
2022
pubmed:
6
12
2022
medline:
6
12
2022
Statut:
epublish
Résumé
Deaths from colorectal cancer (CRC) are still rising, and various links to etiology have been proposed. However, a direct link between microbial dysbiosis and colorectal cancer has not been postulated. This study aimed to identify the role of microbes in the pathogenesis of colorectal cancer. This systematic review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A systematic search was done considering papers published over the past 12 years, using PubMed, PubMed Central, Cochrane, Google Scholar, and ScienceDirect databases. Studies were selected based on the following predefined eligibility criteria: English-language systematic reviews, meta-analysis, randomized controlled trials (RCTs), and clinical trials, which included papers on microbes playing roles in colorectal cancer with the derived data transferred to a template. Following this, quality assessment was done using each study's relevant assessment tool. The initial search generated 128 studies. From the study, we found the ratio of
Identifiants
pubmed: 36465770
doi: 10.7759/cureus.30893
pmc: PMC9711892
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e30893Informations de copyright
Copyright © 2022, Tabowei et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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