Adverse childhood experiences and premature mortality through mid-adulthood: A five-decade prospective study.
Journal
Lancet regional health. Americas
ISSN: 2667-193X
Titre abrégé: Lancet Reg Health Am
Pays: England
ID NLM: 9918232503006676
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
entrez:
5
12
2022
pubmed:
6
12
2022
medline:
6
12
2022
Statut:
ppublish
Résumé
Adverse childhood experiences (ACEs) can have lasting effects on adult health and survival. In this study, we aimed to examine how the cumulative number and clustering patterns of ACEs were related to premature mortality. Participants ( At the start of the follow-up for mortality in 1979, participants were 12-20 years old (Mean=15·99 years), and within the 38-year follow-up through 2016, 3 344 deaths were observed among the 46 129 CPP offspring. Five latent classes of ACEs were identified. Compared to children with About half of the CPP cohort experienced early life adversities that clustered into four distinct patterns, which were associated with different risk of premature mortality. It is important to deepen our understanding of how specific clusters of childhood adversities affect health and premature mortality to better inform approaches to prevention and interventions.
Sections du résumé
Background
UNASSIGNED
Adverse childhood experiences (ACEs) can have lasting effects on adult health and survival. In this study, we aimed to examine how the cumulative number and clustering patterns of ACEs were related to premature mortality.
Methods
UNASSIGNED
Participants (
Findings
UNASSIGNED
At the start of the follow-up for mortality in 1979, participants were 12-20 years old (Mean=15·99 years), and within the 38-year follow-up through 2016, 3 344 deaths were observed among the 46 129 CPP offspring. Five latent classes of ACEs were identified. Compared to children with
Interpretation
UNASSIGNED
About half of the CPP cohort experienced early life adversities that clustered into four distinct patterns, which were associated with different risk of premature mortality. It is important to deepen our understanding of how specific clusters of childhood adversities affect health and premature mortality to better inform approaches to prevention and interventions.
Identifiants
pubmed: 36467261
doi: 10.1016/j.lana.2022.100349
pmc: PMC9718480
mid: NIHMS1829574
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Intramural NIH HHS
ID : ZIA HD008976
Pays : United States
Déclaration de conflit d'intérêts
Declaration of interests All authors declare no competing interests.
Références
Curr Dir Psychol Sci. 2016 Aug;25(4):239-245
pubmed: 27773969
Epidemiology. 2019 Mar;30(2):246-255
pubmed: 30721168
Matern Child Health J. 2018 Mar;22(3):288-297
pubmed: 28929420
Soc Sci Med (1967). 1968 Sep;2(3):283-99
pubmed: 5760819
Acad Pediatr. 2017 Sep - Oct;17(7S):S51-S69
pubmed: 28865661
PLoS One. 2018 Dec 12;13(12):e0208088
pubmed: 30540843
Ann N Y Acad Sci. 1998 May 1;840:33-44
pubmed: 9629234
J Am Heart Assoc. 2020 May 5;9(9):e015326
pubmed: 32342717
Eur J Epidemiol. 2013 Sep;28(9):721-34
pubmed: 23887883
Soc Sci Med. 2019 Nov;240:112566
pubmed: 31585378
Behav Res Ther. 2019 Jul;118:101-109
pubmed: 31030002
Child Abuse Negl. 2015 Oct;48:13-21
pubmed: 26259971
Child Maltreat. 2017 Feb;22(1):58-68
pubmed: 27920222
Annu Rev Dev Psychol. 2019 Dec;1:277-312
pubmed: 32455344
Child Abuse Negl. 2019 Nov;97:104127
pubmed: 31454589
Child Maltreat. 2018 May;23(2):111-125
pubmed: 29113506
Am J Prev Med. 2009 Nov;37(5):389-96
pubmed: 19840693
Addict Behav. 2018 Mar;78:187-192
pubmed: 29179155
JAMA. 2020 Jun 16;323(23):2379-2380
pubmed: 32463425
Curr Opin Psychiatry. 2021 May 1;34(3):306-323
pubmed: 33587493
J Public Health (Oxf). 2015 Sep;37(3):445-54
pubmed: 25174044
Lancet. 2020 Aug 15;396(10249):489-497
pubmed: 32798491
Am Psychol. 2021 Feb-Mar;76(2):203-215
pubmed: 33734789
Am Psychol. 2021 Feb-Mar;76(2):230-242
pubmed: 33734791
Psychoneuroendocrinology. 2020 Jan;111:104492
pubmed: 31704635
JAMA Cardiol. 2021 Feb 1;6(2):228-235
pubmed: 33263716
JAMA Pediatr. 2021 Dec 1;175(12):1269-1278
pubmed: 34605870
Am J Prev Med. 1998 May;14(4):245-58
pubmed: 9635069
Lancet Reg Health Eur. 2021 Nov 30;13:100279
pubmed: 35199082
Brain Behav Immun. 2020 Jul;87:820-830
pubmed: 32201253
Lancet Public Health. 2017 Aug;2(8):e356-e366
pubmed: 29253477