Concurrent light chain amyloidosis and proximal tubulopathy: Insights into different aggregation behavior-A case report.
AL amyloidosis
case report
light chain proximal tubulopathy
monoclonal gammopathy of renal significance
Journal
EJHaem
ISSN: 2688-6146
Titre abrégé: EJHaem
Pays: United States
ID NLM: 101761942
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
received:
06
08
2022
revised:
02
08
2022
accepted:
12
08
2022
entrez:
5
12
2022
pubmed:
6
12
2022
medline:
6
12
2022
Statut:
epublish
Résumé
Due to differences in the protein folding mechanisms, it is exceedingly rare for amyloid light chain (AL) amyloidosis and monoclonal gammopathy of renal significance (MGRS) to coexist. We herein report the first case of concurrent AL amyloidosis and a subclass of MGRS, light chain proximal tubulopathy (LCPT). The 53-year-old female was diagnosed with smoldering myeloma immunoglobulin G
Identifiants
pubmed: 36467828
doi: 10.1002/jha2.555
pii: JHA2555
pmc: PMC9713218
doi:
Types de publication
Case Reports
Langues
eng
Pagination
1377-1380Informations de copyright
© 2022 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd.
Déclaration de conflit d'intérêts
The authors declare they have no conflicts of interest.
Références
Orphanet J Rare Dis. 2012 Aug 21;7:54
pubmed: 22909024
Blood. 2018 Oct 4;132(14):1478-1485
pubmed: 30012636
N Engl J Med. 1991 Jun 27;324(26):1845-51
pubmed: 1904132
Clin Exp Nephrol. 2009 Dec;13(6):671-6
pubmed: 19728011
Nephrol Dial Transplant. 2010 Apr;25(4):1340-3
pubmed: 20061318
Blood. 2020 Oct 1;136(14):1645-1656
pubmed: 32559766
Nat Rev Nephrol. 2019 Jan;15(1):45-59
pubmed: 30510265
Kidney Int. 2022 Jan;101(1):152-163
pubmed: 34767832
Am J Hematol. 2017 Aug;92(8):739-745
pubmed: 28383130
Mod Pathol. 2011 Nov;24(11):1462-9
pubmed: 21701535
Histopathology. 1986 Oct;10(10):1065-76
pubmed: 3096869
J Hepatol. 1991 Jan;12(1):75-82
pubmed: 1901075
Histopathology. 1986 Oct;10(10):1057-64
pubmed: 3096868
Int J Clin Exp Pathol. 2019 Jun 01;12(6):2279-2283
pubmed: 31934052