Patterns of Surgical Recurrence in Patients with Hidradenitis Suppurativa.


Journal

Dermatology (Basel, Switzerland)
ISSN: 1421-9832
Titre abrégé: Dermatology
Pays: Switzerland
ID NLM: 9203244

Informations de publication

Date de publication:
2023
Historique:
received: 02 05 2022
accepted: 01 10 2022
pubmed: 6 12 2022
medline: 7 3 2023
entrez: 5 12 2022
Statut: ppublish

Résumé

Surgery is an essential part of hidradenitis suppurativa (HS) treatment. Understanding and reducing surgical recurrence are crucial to obtaining the best results in patients' treatment. The aim of the study was to characterize surgical recurrences in a cohort of patients with HS treated with wide excision and second-intention healing. A prospective nested case-control study was conducted. A cohort of patients with HS treated with wide excision and second-intention healing was monitored for 68 weeks. The surgical procedure was classified as case (recurrence) or control (no recurrence). The type of recurrence was classified according to the elementary lesion in tunnel or abscess and inflammatory nodule (AN) recurrence. Sociodemographic and clinical data likely related to recurrence and the type of recurrence were evaluated. Sixty-three patients were included, receiving a total of 82 surgical procedures. The mean age of the patients was 36.18 years, and the surgical site presented a Hurley stage II severity in 79.26% (65/82) of the interventions. Tunnel recurrence was observed in 8.5% (7/82) and AN recurrence in 15.85% (13/82) of the interventions. Obesity was associated with a higher risk of recurrence, for both tunnel and AN recurrence. Hurley III at the surgical site, a history of pilonidal sinus, and higher International Hidradenitis Suppurativa Severity Score System (IHS4) after surgery and at week 68 increased the risk of tunnel recurrence. We propose classifying surgical recurrence based on the elemental type of lesion. Tunnel recurrence could originate in the depth of the surgical scar and could be associated with both surgical site factors and inflammatory load. AN recurrence could originate in the borders of the surgical scar and may particularly benefit from preoperative ultrasound.

Sections du résumé

BACKGROUND BACKGROUND
Surgery is an essential part of hidradenitis suppurativa (HS) treatment. Understanding and reducing surgical recurrence are crucial to obtaining the best results in patients' treatment.
OBJECTIVE OBJECTIVE
The aim of the study was to characterize surgical recurrences in a cohort of patients with HS treated with wide excision and second-intention healing.
METHODS METHODS
A prospective nested case-control study was conducted. A cohort of patients with HS treated with wide excision and second-intention healing was monitored for 68 weeks. The surgical procedure was classified as case (recurrence) or control (no recurrence). The type of recurrence was classified according to the elementary lesion in tunnel or abscess and inflammatory nodule (AN) recurrence. Sociodemographic and clinical data likely related to recurrence and the type of recurrence were evaluated.
RESULTS RESULTS
Sixty-three patients were included, receiving a total of 82 surgical procedures. The mean age of the patients was 36.18 years, and the surgical site presented a Hurley stage II severity in 79.26% (65/82) of the interventions. Tunnel recurrence was observed in 8.5% (7/82) and AN recurrence in 15.85% (13/82) of the interventions. Obesity was associated with a higher risk of recurrence, for both tunnel and AN recurrence. Hurley III at the surgical site, a history of pilonidal sinus, and higher International Hidradenitis Suppurativa Severity Score System (IHS4) after surgery and at week 68 increased the risk of tunnel recurrence.
CONCLUSION CONCLUSIONS
We propose classifying surgical recurrence based on the elemental type of lesion. Tunnel recurrence could originate in the depth of the surgical scar and could be associated with both surgical site factors and inflammatory load. AN recurrence could originate in the borders of the surgical scar and may particularly benefit from preoperative ultrasound.

Identifiants

pubmed: 36470224
pii: 000527400
doi: 10.1159/000527400
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

255-261

Informations de copyright

© 2022 S. Karger AG, Basel.

Auteurs

Carlos Cuenca-Barrales (C)

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Instituto de Investigación Biosanitaria GRANADA, Granada, Spain.

Trinidad Montero-Vílchez (T)

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain, tmonterov@gmail.com.
Instituto de Investigación Biosanitaria GRANADA, Granada, Spain, tmonterov@gmail.com.

Manuel Sanchez-Diaz (M)

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.

Juan-Ángel Rodríguez-Pozo (JÁ)

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.

Pablo Díaz-Calvillo (P)

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.

Antonio Martinez-Lopez (A)

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Instituto de Investigación Biosanitaria GRANADA, Granada, Spain.

Salvador Arias-Santiago (S)

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Instituto de Investigación Biosanitaria GRANADA, Granada, Spain.

Alejandro Molina-Leyva (A)

Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Instituto de Investigación Biosanitaria GRANADA, Granada, Spain.
European Hidradenitis Suppurativa Foundation (EHSF), Dessau-Roßlau, Germany.
Grupo Español de Hidradenitis Supurativa, Academia Española de Dermatología y Venereologia, Madrid, Spain.

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Classifications MeSH