Artificial Intelligence for Clinical Interpretation of Bedside Chest Radiographs.


Journal

Radiology
ISSN: 1527-1315
Titre abrégé: Radiology
Pays: United States
ID NLM: 0401260

Informations de publication

Date de publication:
04 2023
Historique:
medline: 29 3 2023
pubmed: 7 12 2022
entrez: 6 12 2022
Statut: ppublish

Résumé

Background Supine chest radiography for bedridden patients in intensive care units (ICUs) is one of the most frequently ordered imaging studies worldwide. Purpose To evaluate the diagnostic performance of a neural network-based model that is trained on structured semiquantitative radiologic reports of bedside chest radiographs. Materials and Methods For this retrospective single-center study, children and adults in the ICU of a university hospital who had been imaged using bedside chest radiography from January 2009 to December 2020 were reported by using a structured and itemized template. Ninety-eight radiologists rated the radiographs semiquantitatively for the severity of disease patterns. These data were used to train a neural network to identify cardiomegaly, pulmonary congestion, pleural effusion, pulmonary opacities, and atelectasis. A held-out internal test set (100 radiographs from 100 patients) that was assessed independently by an expert panel of six radiologists provided the ground truth. Individual assessments by each of these six radiologists, by two nonradiologist physicians in the ICU, and by the neural network were compared with the ground truth. Separately, the nonradiologist physicians assessed the images without and with preliminary readings provided by the neural network. The weighted Cohen κ coefficient was used to measure agreement between the readers and the ground truth. Results A total of 193 566 radiographs in 45 016 patients (mean age, 66 years ± 16 [SD]; 61% men) were included and divided into training (

Identifiants

pubmed: 36472534
doi: 10.1148/radiol.220510
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e220510

Commentaires et corrections

Type : CommentIn

Auteurs

Firas Khader (F)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Tianyu Han (T)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Gustav Müller-Franzes (G)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Luisa Huck (L)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Philipp Schad (P)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Sebastian Keil (S)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Emona Barzakova (E)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Maximilian Schulze-Hagen (M)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Federico Pedersoli (F)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Volkmar Schulz (V)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Markus Zimmermann (M)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Lina Nebelung (L)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Jakob Kather (J)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Karim Hamesch (K)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Christoph Haarburger (C)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Gernot Marx (G)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Johannes Stegmaier (J)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Christiane Kuhl (C)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Philipp Bruners (P)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Sven Nebelung (S)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

Daniel Truhn (D)

From the Department of Diagnostic and Interventional Radiology (F.K., G.M.F., L.H., P.S., S.K., E.B., M.S.H., F.P., M.Z., C.K., P.B., S.N., D.T.), Department of Medicine III (J.K., K.H.), and Clinic for Surgical Intensive Medicine and Intermediate Care (G.M.), University Hospital Aachen, Pauwelsstrasse 30, 52064 Aachen, Germany; Physics of Molecular Imaging Systems, Experimental Molecular Imaging (T.H., V.S.), and Institute of Imaging and Computer Vision (J.S.), RWTH Aachen University, Aachen, Germany; Department of Inner Medicine, Luisenhospital Aachen, Aachen, Germany (L.N.); and Ocumeda AG, Erlen, Switzerland (C.H.).

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