A Generalized Form of Lichen Planus Pemphigoid Induced by an Oral Antidiabetic.
bullous skin disease
gliclazide
induced
lichen planus pemphigoid
sulphonylurea oral hypoglycaemic
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
accepted:
02
11
2022
entrez:
7
12
2022
pubmed:
8
12
2022
medline:
8
12
2022
Statut:
epublish
Résumé
Lichen planus pemphigoid (LPP) is a rare autoimmune bullous dermatosis, although it is frequently idiopathic, the induced form is rare and there are few inducing drugs. We report a case of LPP induced by a gliclazide. A 68-year-old female patient with type 2 diabetes on gliclazide for three months presented with an eight-week history of generalized erythematous-papular eruption. Then she developed blisters on her forearms with oral mucosa involvement. A diagnosis of gliclazide-induced LPP was made based on a skin biopsy and imputability. The patient was treated with systemic corticosteroid with an improvement. LPP is a rare entity; its diagnosis is a challenge as it represents an overlap between lichen planus and bullous pemphigoid.
Identifiants
pubmed: 36475211
doi: 10.7759/cureus.31094
pmc: PMC9719724
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e31094Informations de copyright
Copyright © 2022, Ajaaouani et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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