3D organ-on-a-chip: The convergence of microphysiological systems and organoids.
3D bioprinting
drug development
microfluidics
organ on a chip
organoids
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2022
2022
Historique:
received:
13
09
2022
accepted:
07
11
2022
entrez:
8
12
2022
pubmed:
9
12
2022
medline:
9
12
2022
Statut:
epublish
Résumé
Medicine today faces the combined challenge of an increasing number of untreatable diseases and fewer drugs reaching the clinic. While pharmaceutical companies have increased the number of drugs in early development and entering phase I of clinical trials, fewer actually successfully pass phase III and launch into the market. In fact, only 1 out of every 9 drugs entering phase I will launch.
Identifiants
pubmed: 36478741
doi: 10.3389/fcell.2022.1043117
pii: 1043117
pmc: PMC9720174
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1043117Informations de copyright
Copyright © 2022 Baptista, Porrini, Kronemberger, Kelly and Perrault.
Déclaration de conflit d'intérêts
LB was a Marie-Curie fellowship at Eden Tech. CP and CMP were employed by Eden Tech. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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