Utility of 5-aminolaevulinic acid fluorescence-guided endoscopic biopsy for malignant mesothelioma in a cat and dog.
cat
chemotherapy
dog
laparoscopy
thoracoscopy
Journal
Australian veterinary journal
ISSN: 1751-0813
Titre abrégé: Aust Vet J
Pays: England
ID NLM: 0370616
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
revised:
02
11
2022
received:
06
09
2022
accepted:
24
11
2022
pubmed:
10
12
2022
medline:
4
3
2023
entrez:
9
12
2022
Statut:
ppublish
Résumé
Malignant mesothelioma (MM) is uncommon in cats and dogs and can be challenging to diagnose. Adequate tissue sampling is required for superior diagnostic accuracy. Protoporphyrin IX, a metabolite of 5-aminolaevulinic acid (5-ALA), is a photosensitiser for photodynamic diagnosis (PDD). To the best of our knowledge, no study has reported the use of 5-ALA-PDD to detect MM in veterinary medicine. The present study describes the use of 5-ALA-PDD for MM diagnosis in a cat and dog, as well as the effectiveness of intracavitary chemotherapy. We evaluated the use of PDD with 5-ALA hydrochloride (5-ALA-PDD) in two cases of MM. A 12-year-old cat presented with a 1-month history of respiratory distress, and a 9-year-old dog presented with a 3-month history of mild abdominal distention. We endoscopically biopsied lesions in both the cases using 5-ALA-PDD. Histopathological examination revealed mesothelioma, and immunohistochemical staining was positive for calretinin. Both patients were treated with carboplatin. The cat died of respiratory failure. Although, the dog's condition improved 21 days after the first chemotherapeutic drug administration, the dog died on day 684 owing to cardiac-related issues. 5-ALA-PDD is thus, safe and feasible for the diagnosis of MM in veterinary medicine.
Substances chimiques
Aminolevulinic Acid
88755TAZ87
Photosensitizing Agents
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
99-105Subventions
Organisme : SBI Pharmaceuticals, Tokyo, Japan
Informations de copyright
© 2022 Australian Veterinary Association.
Références
Merlo WA, Rosciani AS. Mesothelioma in domestic animals. In: Zurbritsky A, editor. Cytological and anatomopathological aspects mesotheliomas - synonyms and definition, epidemiology, etiology, pathogenesis, Cyto-histopathological features, clinic, diagnosis, treatment, prognosis. IntecOpen, London, UK, 2012;87-96.
Bacci B, Morandi F, De Meo M et al. Ten cases of feline mesothelioma: An immunohistochemical and ultrastructural study. J Comp Pathol 2006;134:347-354. https://doi.org/10.1016/j.jcpa.2006.02.001.
Cakir E, Demirag F, Aydin M et al. Cytopathologic differential diagnosis of malignant mesothelioma, adenocarcinoma and reactive mesothelial cells: A logistic regression analysis. Diagn Cytopathol 2009;37:4-10. https://doi.org/10.1002/dc.20938.
Balsa IM, Culp WTN. Use of minimally invasive surgery in the diagnosis and treatment of cancer in dogs and cats. Vet Sci 2019;6:E33. https://doi.org/10.3390/vetsci6010033.
Attanoos RL, Gibbs AR. The comparative accuracy of different pleural biopsy techniques in the diagnosis of malignant mesothelioma. Histopathology 2008;53:340-344. https://doi.org/10.1111/j.1365-2559.2008.03099.x.
Ishizuka M, Abe F, Sano Y et al. Novel development of 5-aminolevurinic acid (ALA) in cancer diagnoses and therapy. Int Immunopharmacol 2011;11:358-365. https://doi.org/10.1016/j.intimp.2010.11.029.
Koizumi N, Harada Y, Minamikawa T et al. Recent advances in photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid. World J Gastroenterol 2016;22:1289-1296. https://doi.org/10.3748/wjg.v22.i3.1289.
Osaki T, Yokoe I, Ogura S et al. Photodynamic detection of canine mammary gland tumours after oral administration of 5-aminolevulinic acid. Vet Comp Oncol 2017;15:731-739. https://doi.org/10.1111/vco.12213.
Osaki T, Yokoe I, Sunden Y et al. Efficacy of 5-aminolevulinic acid in photodynamic detection and photodynamic therapy in veterinary medicine. Cancers (Basel) 2019;11:E495. https://doi.org/10.3390/cancers11040495.
Osaki T, Gonda K, Murahata Y et al. Photodynamic detection of a feline meningioma using 5-aminolaevulinic acid hydrochloride. JFMS Open Rep 2020;6:2055116920907429. https://doi.org/10.1177/2055116920907429.
Yonemura Y, Endo Y, Canbay E et al. Selection of patients by membrane transporter expressions for aminolevulinic acid (ALA)-guided photodynamic detection of peritoneal metastases. Int J Sci 2015;4:66-77.
Liu Y, Endo Y, Fujita T et al. Cytoreductive surgery under aminolevulinic acid-mediated photodynamic diagnosis plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from ovarian cancer and primary peritoneal carcinoma: Results of a phase I trial. Ann Surg Oncol 2014;21:4256-4262. https://doi.org/10.1245/s10434-014-3901-5.
de Bree E, Michelakis D, Stamatiou D et al. Pharmacological principles of intraperitoneal and bidirectional chemotherapy. Pleura Peritoneum 2017;2:47-62. https://doi.org/10.1515/pp-2017-0010.
Hartmann HF, Oliveira MTDE, JPS F et al. Thoracoscopic pericardiectomy associated with fully implantable catheter via thoracoscopy in the management of mesothelioma in a bitch. J Vet Med Sci 2019;81:946-948. https://doi.org/10.1292/jvms.17-0631.
Los G, Verdegaal EM, Mutsaers PH et al. Penetration of carboplatin and cisplatin into rat peritoneal tumor nodules after intraperitoneal chemotherapy. Cancer Chemother Pharmacol 1991;28:159-165. https://doi.org/10.1007/BF00685503.